Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Department of Psychiatry and Psychology, Mayo Clinic, Scottsdale, Arizona, USA.
Headache. 2023 Jun;63(6):743-750. doi: 10.1111/head.14518. Epub 2023 May 23.
Our objectives were to examine cross-sectional correlations of headache disability with measures of resilience, anxiety, and depression, and to determine if resilience modified the association between headache severity/frequency and disability.
Resilience is associated with quality of life and functioning among patients with chronic conditions. We investigated whether resilience strongly mitigates headache-related disability as measured by the Migraine Disability Assessment (MIDAS).
We prospectively recruited 160 patients with primary headache disorders seen in a tertiary headache medicine program between February 20, 2018 and August 2, 2019. Each participant completed the MIDAS, Conner Davidson Resilience Scale (CDRS-25), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and WHO-5 Well-Being Index.
The CDRS-25 score was negatively correlated with the total MIDAS (r = -0.21, p = 0.009), GAD-7 (r = -0.56, p < 0.001), and PHQ-9 scores (r = -0.34, p < 0.001). Well-being inversely correlated with disability (r = -0.37, p < 0.001). Increases in anxiety and depression increased the odds of disability. A 1 point increase in the CDRS-25 score decreased the odds of being severely disabled by 4% (OR = 0.96, 95% CI: 0.94 to 0.99, p = 0.001). However, the CDRS-25 score did not significantly moderate the association between headache days and disability.
Traits associated with resilience decreased the odds of severe disability from headaches, whereas anxiety, depression, and headache frequency were strongly associated with higher disability from headache.
本研究旨在探讨头痛残疾与韧性、焦虑和抑郁测量指标的横断面相关性,并确定韧性是否能改变头痛严重程度/频率与残疾之间的关联。
韧性与慢性疾病患者的生活质量和功能有关。我们调查了韧性是否能显著减轻偏头痛残疾评估(MIDAS)所衡量的与头痛相关的残疾。
我们前瞻性招募了 2018 年 2 月 20 日至 2019 年 8 月 2 日期间在三级头痛医学项目中就诊的原发性头痛障碍患者 160 例。每位参与者完成了 MIDAS、康纳戴维森韧性量表(CDRS-25)、患者健康问卷-9(PHQ-9)、广泛性焦虑障碍-7(GAD-7)和世界卫生组织-5 幸福感指数。
CDRS-25 评分与 MIDAS 总分(r = -0.21,p = 0.009)、GAD-7(r = -0.56,p < 0.001)和 PHQ-9 评分(r = -0.34,p < 0.001)呈负相关。幸福感与残疾呈负相关(r = -0.37,p < 0.001)。焦虑和抑郁的增加增加了残疾的几率。CDRS-25 评分增加 1 分,严重残疾的几率降低 4%(OR = 0.96,95%CI:0.94 至 0.99,p = 0.001)。然而,CDRS-25 评分并没有显著调节头痛天数与残疾之间的关系。
与韧性相关的特征降低了因头痛而导致严重残疾的几率,而焦虑、抑郁和头痛频率与因头痛导致的更高残疾率密切相关。