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多体位扫描在超声心动图评估不一致性主动脉瓣狭窄严重程度中的优势

Advantages of Multiposition Scanning in Echocardiographic Assessment of the Severity of Discordant Aortic Stenosis.

作者信息

Golukhova Elena Zelikovna, Slivneva Inessa Viktorovna, Farulova Inga Yur'evna, Skopin Ivan Ivanovich, Marapov Damir Ildarovich, Murysova Dar'ya Vladimirovna, Pirushkina Yuliya Dmitrievna, Volkovskaya Irina Vasilyevna

机构信息

A.N. Bakulev National Medical Scientific Center for Cardiovascular Surgery, Ministry of Health of the Russian Federation, 121552 Moscow, Russia.

Department of Cardiovascular and Comorbid Pathology, A.N. Bakulev National Medical Scientific Center for Cardiovascular Surgery, Ministry of Health of the Russian Federation, 121552 Moscow, Russia.

出版信息

Pathophysiology. 2023 Apr 26;30(2):174-185. doi: 10.3390/pathophysiology30020015.

Abstract

AIM OF THE STUDY

The aim of this study was to perform a comparative analysis of severity of discordant aortic stenosis (AS) assessment using multiposition scanning and the standard apical window.

MATERIALS AND METHODS

All patients ( = 104) underwent preoperative transthoracic echocardiography (TTE) and were ranked according to the degree of AS severity. The reproducibility feasibility of the right parasternal window (RPW) was 75.0% ( = 78). The mean age of the patients was 64 years, and 40 (51.3%) were female. In 25 cases, low gradients were identified from the apical window not corresponding to the visual structural changes in the aortic valve, or disagreement between the velocity and calculated parameters was detected. Patients were divided into two groups: concordant AS ( = 56; 71.8%) and discordant AS ( = 22; 28.2%). Three individuals were excluded from the discordant AS group due to the presence of moderate stenosis.

RESULTS

Based on the comparative analysis of transvalvular flow velocities obtained from multiposition scanning, the concordance group showed agreement between the velocity and calculated parameters. We observed an increase in the mean transvalvular pressure gradient (ΔP) and peak aortic jet velocity (V), ΔP in 95.5% of patients, velocity time integral of transvalvular flow (VTI AV) in 90.9% of patients, and a decrease in aortic valve area (AVA) and indexed AVA in 90.9% of patients after applying RPW in all patients with discordant AS. The use of RPW allowed the reclassification of AS severity from discordant to concordant high-gradient AS in 88% of low-gradient AS cases.

CONCLUSION

Underestimation of flow velocity and overestimation of AVA using the apical window may lead to misclassification of AS. The use of RPW helps to match the degree of AS severity with the velocity characteristics and reduce the number of low-gradient AS cases.

摘要

研究目的

本研究旨在对使用多体位扫描和标准心尖窗评估不一致性主动脉瓣狭窄(AS)的严重程度进行对比分析。

材料与方法

所有患者(n = 104)均接受术前经胸超声心动图(TTE)检查,并根据AS严重程度进行排序。右胸骨旁窗(RPW)的可重复性可行性为75.0%(n = 78)。患者的平均年龄为64岁,40例(51.3%)为女性。在25例病例中,从心尖窗识别出低梯度,这与主动脉瓣的视觉结构变化不对应,或者检测到速度与计算参数之间存在不一致。患者分为两组:一致性AS(n = 56;71.8%)和不一致性AS(n = 22;28.2%)。由于存在中度狭窄,三名个体被排除在不一致性AS组之外。

结果

基于从多体位扫描获得的跨瓣血流速度的对比分析,一致性组显示速度与计算参数之间具有一致性。在所有不一致性AS患者中应用RPW后,我们观察到平均跨瓣压力阶差(ΔP)和主动脉峰值射流速度(V)增加,95.5%的患者ΔP增加,90.9%的患者跨瓣血流速度时间积分(VTI AV)增加,90.9%的患者主动脉瓣面积(AVA)和指数化AVA减小。在88%的低梯度AS病例中,使用RPW可将AS严重程度从不一致重新分类为一致性高梯度AS。

结论

使用心尖窗时血流速度低估和AVA高估可能导致AS的错误分类。使用RPW有助于使AS严重程度与速度特征相匹配,并减少低梯度AS病例的数量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36d5/10204481/1e51c2c4b7a2/pathophysiology-30-00015-g001.jpg

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