Unit of Infectious and Tropical Diseases, Department of Clinical and Experimental Sciences, University of Brescia and ASST Spedali Civili di Brescia, 25123 Brescia, Italy.
Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia and ASST Spedali Civili of Brescia, 25123 Brescia, Italy.
Tomography. 2023 Apr 23;9(3):894-900. doi: 10.3390/tomography9030073.
X-linked agammaglobulinemia (XLA) is a primary immunodeficiency characterized by marked reduction in serum immunoglobulins and early-onset infections. Coronavirus Disease-2019 (COVID-19) pneumonia in immunocompromised patients presents clinical and radiological peculiarities which have not yet been completely understood. Very few cases of agammaglobulinemic patients with COVID-19 have been reported since the beginning of the pandemic in February 2020. We report two cases of migrant COVID-19 pneumonia in XLA patients.
X 连锁无丙种球蛋白血症(XLA)是一种以血清免疫球蛋白显著减少和早期感染为特征的原发性免疫缺陷病。免疫功能低下患者的 2019 冠状病毒病(COVID-19)肺炎具有尚未完全了解的临床和影像学特征。自 2020 年 2 月大流行开始以来,报告的 COVID-19 伴无丙种球蛋白血症患者的病例非常少。我们报告了 2 例 XLA 患者的移民 COVID-19 肺炎病例。