Herrera-Restrepo Oscar, Kuang Yuting, D'Angelo John, Bekkat-Berkani Rafik, Clements Diana E, Uyei Jennifer
GSK, FMC Tower Suite 1700, 2929 Walnut Street, Philadelphia, PA, 19104, USA.
IQVIA, San Francisco, USA.
Infect Dis Ther. 2023 May;12(5):1265-1282. doi: 10.1007/s40121-023-00793-2. Epub 2023 May 22.
We conducted a targeted literature review to understand the determinants of meningococcal serogroups A, C, W, and Y (MenACWY) and meningococcal serogroup B (MenB) vaccination coverage and adherence to vaccination schedules in the USA, and to identify evidence to support improvement of MenACWY and MenB vaccination coverage and adherence in older adolescents. Sources published since 2011 were considered, with sources published since 2015 given preference. Out of 2355 citations screened, 47 (46 studies) were selected for inclusion. Determinants of coverage and adherence ranging from patient-level sociodemographic factors to policy-level factors were identified. Four determinants identified were associated with improved coverage and adherence: (1) well-child, preventive, or vaccination-only appointments (particularly for older adolescents); (2) provider-initiated, provider-driven vaccine recommendations; (3) provider education about meningococcal disease and vaccine recommendations; and (4) state-level school-entry immunization policies. This robust review of the literature sheds light on the continued low MenACWY and MenB vaccination coverage and adherence among older adolescents (16-23 years of age) compared with that of younger adolescents (11-15 years of age) in the USA. The evidence supports a renewed call to action by local and national health authorities and medical organizations urging healthcare professionals to implement a healthcare visit for 16-year-olds and focus on vaccination as a key component of the visit.
我们进行了一项针对性的文献综述，以了解美国A、C、W和Y群脑膜炎球菌（MenACWY）及B群脑膜炎球菌（MenB）疫苗接种覆盖率和疫苗接种计划依从性的决定因素，并找出支持提高大龄青少年MenACWY和MenB疫苗接种覆盖率及依从性的证据。我们纳入了自2011年以来发表的文献，并优先考虑自2015年以来发表的文献。在筛选的2355篇文献中，有47篇（46项研究）被选中纳入。我们确定了从患者层面的社会人口学因素到政策层面因素等一系列影响覆盖率和依从性的决定因素。确定的四个决定因素与提高覆盖率和依从性相关：（1）健康儿童、预防性或仅接种疫苗的预约（特别是针对大龄青少年）；（2）由医疗服务提供者发起、主导的疫苗推荐；（3）医疗服务提供者关于脑膜炎球菌病和疫苗推荐的教育；（4）州级入学免疫政策。这项对文献的全面综述揭示了在美国，与低龄青少年（11 - 15岁）相比，大龄青少年（16 - 23岁）的MenACWY和MenB疫苗接种覆盖率及依从性持续较低的情况。这些证据支持地方和国家卫生当局以及医疗组织再次呼吁采取行动，敦促医疗保健专业人员为16岁青少年安排一次医疗就诊，并将疫苗接种作为就诊的关键组成部分。
