Gelman Justin C, Shutran Max, Young Michael, Taussky Philipp, Vega Rafael A, Armonda Rocco, Ogilvy Christopher S
Harvard Medical School, Boston, Massachusetts, USA.
Neurosurgical Service, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
J Cerebrovasc Endovasc Neurosurg. 2023 Dec;25(4):434-439. doi: 10.7461/jcen.2023.E2022.11.001. Epub 2023 May 24.
Pseudoaneurysms are rare but devastating complications of penetrating head traumas. They require rapid surgical or endovascular intervention due to their high risk of rupture; however, complex presentations may limit treatment options. Our objective is to report a case of severe vasospasm, flow diversion, and in-stent stenosis complicating the treatment of a middle cerebral artery pseudoaneurysm following a gunshot wound. A 33-year-old woman presented with multiple calvarial and bullet fragments within the right frontotemporal lobes and a large right frontotemporal intraparenchymal hemorrhage with significant cerebral edema. She underwent an emergent right hemicraniectomy for decompression, removal of bullet fragments, and evacuation of hemorrhage. Once stable enough for diagnostic cerebral angiography, she was found to have an M1 pseudoaneurysm with severe vasospasm that precluded endovascular treatment until the vasospasm resolved. The pseudoaneurysm was treated with flow diversion and in-stent stenosis was found at 4-month follow-up angiography that resolved by 8 months post-embolization. We report the successful flow diversion of an middle cerebral artery (MCA) pseudoaneurysm complicated by severe vasospasm and later in-stent stenosis. The presence of asymptomatic stenosis is believed to be reversible intimal hyperplasia and a normal aspect of endothelial healing. We suggest careful observation and dual-antiplatelet therapy as a justified approach.
假性动脉瘤是穿透性颅脑外伤罕见但极具破坏性的并发症。由于其破裂风险高,需要迅速进行外科手术或血管内介入治疗;然而,复杂的临床表现可能会限制治疗选择。我们的目的是报告一例因枪伤导致大脑中动脉假性动脉瘤治疗后出现严重血管痉挛、血流改道和支架内狭窄的病例。一名33岁女性因右侧额颞叶内有多个颅骨和子弹碎片,以及右侧额颞叶脑实质内大量出血并伴有明显脑水肿而就诊。她接受了紧急右侧颅骨切除术以减压、清除子弹碎片并引流出血液。一旦病情稳定到足以进行诊断性脑血管造影,发现她有一个M1假性动脉瘤,伴有严重血管痉挛,在血管痉挛缓解之前无法进行血管内治疗。该假性动脉瘤采用血流改道治疗,在4个月的随访血管造影中发现支架内狭窄,栓塞后8个月狭窄消失。我们报告了一例成功进行血流改道治疗的大脑中动脉(MCA)假性动脉瘤,该病例伴有严重血管痉挛和后期支架内狭窄。无症状狭窄的出现被认为是可逆的内膜增生,是内皮愈合的正常表现。我们建议仔细观察并采用双联抗血小板治疗作为一种合理方法。