Sithole B B, Williams D T, Lastoria C, Robertson J L
J Assoc Off Anal Chem. 1986 May-Jun;69(3):466-73.
Pentafluorobenzylation and in situ acetylation are compared in the determination of phenol and halogenated phenols in water samples. The latter technique is considered superior to the former for determining phenols at the ng/L level because of less background interference and better recoveries (80% or better except for pentachlorophenol and trichloroguaiacol which had recoveries of about 60%). Further evaluation of the in situ technique by electron capture gas chromatography and gas chromatography-mass spectrometry shows that the latter, in the selected ion monitoring mode, is more suitable because, unlike GC-ECD, it can confirm and quantitate all phenols. In particular, GC-ECD could not detect even high levels of phenol and the monohalogenated phenols. Phenols at 5-473 ng/L were detected in some Canadian drinking water supplies by the in situ acetylation technique combined with GC-MS.
在水样中苯酚和卤代酚的测定中，对五氟苄基化和原位乙酰化进行了比较。由于背景干扰较少且回收率更高（除五氯苯酚和三氯愈创木酚的回收率约为60%外，其他酚类的回收率为80%或更高），后一种技术在测定纳克/升水平的酚类时被认为优于前一种技术。通过电子捕获气相色谱法和气相色谱-质谱法对原位技术的进一步评估表明，在选择离子监测模式下，气相色谱-质谱法更适用，因为与气相色谱-电子捕获检测器不同，它可以对所有酚类进行确证和定量。特别是，气相色谱-电子捕获检测器甚至无法检测到高浓度的苯酚和单卤代酚。通过原位乙酰化技术结合气相色谱-质谱法，在一些加拿大饮用水供应中检测到了浓度为5-473纳克/升的酚类。
