Department of Midwifery, School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Reproductive Health Promotion Research Center, Department of Midwifery, School of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
BMC Psychiatry. 2023 May 23;23(1):357. doi: 10.1186/s12888-023-04870-1.
Hypothyroidism is the most common clinical disorder of the thyroid gland which is associated with an increased prevalence of sexual dysfunction even if treated with medication.
The aim of this study was to determine the effect of cognitive-behavioral therapy (CBT) on sexual function in reproductive-aged women with hypothyroidism.
This randomized clinical trial was performed on 66 reproductive-aged women with hypothyroidism referring to selected health centers in Izeh, Iran. Data collection tools included demographic information form and Female Sexual Function Index (FSFI). Eligible individuals were randomly assigned to case (n = 33) and control (n = 33) groups using block randomization with the block size of 4. In addition to standard hypothyroidism treatment, the case group received 8 sessions of cognitive-behavioral group therapy, while the control group received only standard treatment.
Before of treatment, there was no significant difference between the mean score of sexual function and its dimensions between the case and control groups (p < 0.05). However, immediately and 4 weeks after completion of treatment, the mean total score of sexual function and its dimensions in the case group increased significantly compared to the control group (p < 0.001).
According to the results of this study, CBT can be effective in improving sexual dysfunction in reproductive-aged women with hypothyroidism. However, before recommending this therapy to women suffering from hypothyroidism, more detailed studies are needed to prove the effectiveness of this intervention, as an adjuvant treatment to the standard pharmacotherapy.
甲状腺功能减退症是甲状腺最常见的临床疾病，即使经过药物治疗，其性功能障碍的发病率也会增加。
本研究旨在确定认知行为疗法（CBT）对甲状腺功能减退症育龄妇女性功能的影响。
这是一项随机临床试验，研究对象为 66 名患有甲状腺功能减退症的育龄期伊朗伊泽赫选定健康中心的妇女。数据收集工具包括人口统计学信息表和女性性功能指数（FSFI）。合格的个体采用 4 个块大小的区组随机化方法被随机分配到病例组（n=33）和对照组（n=33）。除了标准的甲状腺功能减退症治疗外，病例组还接受了 8 次认知行为小组治疗，而对照组仅接受标准治疗。
治疗前，病例组和对照组之间性功能及其各维度的平均评分无显著差异（p＞0.05）。然而，在治疗结束后即刻和 4 周时，病例组的性功能及其各维度的总评分明显高于对照组（p＜0.001）。
根据本研究结果，CBT 可有效改善甲状腺功能减退症育龄妇女的性功能障碍。然而，在向患有甲状腺功能减退症的妇女推荐这种治疗方法之前，还需要进行更详细的研究，以证明这种干预措施的有效性，作为标准药物治疗的辅助治疗。
