Development. 2023 May 15;150(10). doi: 10.1242/dev.201966. Epub 2023 May 24.
Hox genes encode a family of conserved transcription factors that play important roles in specifying regions of the body plan along the anterior-posterior axis. A new paper in Development introduces new approaches and provides further insights into the transcriptional mechanisms controlling Hox gene expression during vertebrate development. To hear more about the story behind the paper, we caught up with the first author Zainab Afzal and her PhD supervisor Robb Krumlauf, Professor at the Stowers Institute for Medical Research.
Hox 基因编码一组保守的转录因子，它们在沿身体前后轴特化体节模式区域方面发挥着重要作用。《发育》杂志上的一篇新论文提出了新方法，并进一步深入了解了控制脊椎动物发育过程中 Hox 基因表达的转录机制。为了更多地了解这篇论文背后的故事，我们采访了第一作者 Zainab Afzal 和她的博士导师 Robb Krumlauf，他是斯托尔斯医学研究所的教授。
