• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

对一名有多发性骨髓瘤和乳腺癌病史的患者行全髋关节置换术并预防性固定大转子和股骨远端

Total Hip Arthroplasty With Prophylactic Fixation of Greater Trochanter and Distal Femur in a Patient With a History of Multiple Myeloma and Breast Cancer.

作者信息

Small Tyler, Fox Kevin, Edge Lauren, Harker John

机构信息

Orthopaedic Surgery, Liberty University College of Osteopathic Medicine, Lynchburg, USA.

Orthopaedic Surgery, HCA Healthcare/USF Morsani College of Medicine GME: HCA Florida Largo Hospital, Largo, USA.

出版信息

Cureus. 2023 Apr 22;15(4):e37971. doi: 10.7759/cureus.37971. eCollection 2023 Apr.

DOI:10.7759/cureus.37971
PMID:37223142
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10202678/
Abstract

Multiple myeloma is the most common primary malignancy of the bone marrow and may present as bone pain and/or pathologic fracture(s) in affected patients. Treatment of bone lesions typically consists of chemotherapy and radiation and may include prophylactic fixation in patients meeting specific criteria. This report reviews a case of a 74-year-old female with a history of multiple myeloma and breast cancer, previously treated with chemotherapy and radiation, who sustained a pathologic femoral neck fracture with associated ipsilateral lesions of the femoral shaft and peritrochanteric region. This patient received a total hip arthroplasty with a greater trochanteric claw plate and extended femoral stem for prophylactic fixation of the distal femur. In this report, the current literature surrounding the use of extended femoral stems for prophylactic fixation of femoral diaphyseal lesions will be reviewed and the above case will be presented. This case serves as a bridge between orthopedic oncology and arthroplasty as an extended femoral stem was used to prevent future pathologic fracture of distal femur lesions.

摘要

多发性骨髓瘤是最常见的原发性骨髓恶性肿瘤，在受影响的患者中可能表现为骨痛和/或病理性骨折。骨病变的治疗通常包括化疗和放疗，对于符合特定标准的患者可能包括预防性固定。本报告回顾了一例74岁女性病例，该患者有骨髓瘤和乳腺癌病史，曾接受化疗和放疗，发生了病理性股骨颈骨折，并伴有同侧股骨干和转子周围区域病变。该患者接受了全髋关节置换术，使用了大转子爪形钢板和延长股骨干，以预防性固定股骨远端。在本报告中，将回顾目前关于使用延长股骨干预防性固定股骨干病变的文献，并介绍上述病例。该病例作为骨科肿瘤学和关节置换术之间的桥梁，因为使用了延长股骨干来预防股骨远端病变未来的病理性骨折。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/249cf6e61569/cureus-0015-00000037971-i16.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/5523212f65a1/cureus-0015-00000037971-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/52aaba7993ab/cureus-0015-00000037971-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/7ee09c5fd1ea/cureus-0015-00000037971-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/a35f4134406b/cureus-0015-00000037971-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/bbd1b1f390f3/cureus-0015-00000037971-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/762214059f03/cureus-0015-00000037971-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/463839243f67/cureus-0015-00000037971-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/96bd2fe4c6c2/cureus-0015-00000037971-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/0decbbbfd4e8/cureus-0015-00000037971-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/3021d2a86fb8/cureus-0015-00000037971-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/6005daceb915/cureus-0015-00000037971-i11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/4b4e3cacace2/cureus-0015-00000037971-i12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/0914b26a7cc5/cureus-0015-00000037971-i13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/f3fa0bf754a2/cureus-0015-00000037971-i14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/1d2cc99f4005/cureus-0015-00000037971-i15.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/249cf6e61569/cureus-0015-00000037971-i16.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/5523212f65a1/cureus-0015-00000037971-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/52aaba7993ab/cureus-0015-00000037971-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/7ee09c5fd1ea/cureus-0015-00000037971-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/a35f4134406b/cureus-0015-00000037971-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/bbd1b1f390f3/cureus-0015-00000037971-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/762214059f03/cureus-0015-00000037971-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/463839243f67/cureus-0015-00000037971-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/96bd2fe4c6c2/cureus-0015-00000037971-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/0decbbbfd4e8/cureus-0015-00000037971-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/3021d2a86fb8/cureus-0015-00000037971-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/6005daceb915/cureus-0015-00000037971-i11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/4b4e3cacace2/cureus-0015-00000037971-i12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/0914b26a7cc5/cureus-0015-00000037971-i13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/f3fa0bf754a2/cureus-0015-00000037971-i14.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/1d2cc99f4005/cureus-0015-00000037971-i15.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32b2/10202678/249cf6e61569/cureus-0015-00000037971-i16.jpg

相似文献

1
Total Hip Arthroplasty With Prophylactic Fixation of Greater Trochanter and Distal Femur in a Patient With a History of Multiple Myeloma and Breast Cancer.对一名有多发性骨髓瘤和乳腺癌病史的患者行全髋关节置换术并预防性固定大转子和股骨远端
Cureus. 2023 Apr 22;15(4):e37971. doi: 10.7759/cureus.37971. eCollection 2023 Apr.
2
[Clinical results in early and mid term of using the S-ROM femoral stem in revision].[S-ROM股骨柄在翻修术中应用的早中期临床结果]
Zhongguo Gu Shang. 2017 Apr 25;30(4):322-328. doi: 10.3969/j.issn.1003-0034.2017.04.008.
3
What Is the Adverse Event Profile After Prophylactic Treatment of Femoral Shaft or Distal Femur Metastases?预防性治疗股骨骨干或股骨远端转移后不良事件的概况是什么？
Clin Orthop Relat Res. 2018 Dec;476(12):2381-2388. doi: 10.1097/CORR.0000000000000489.
4
Does Femoral Morphology Predict the Risk of Periprosthetic Fracture After Cementless Total Hip Arthroplasty?股骨形态是否能预测非骨水泥全髋关节置换术后假体周围骨折的风险？
J Arthroplasty. 2020 Jun;35(6S):S359-S363. doi: 10.1016/j.arth.2020.02.048. Epub 2020 Feb 29.
5
Impaction Bone Grafting for Severe Femoral Bone Loss: Surgical Technique in Revision Total Hip Arthroplasty.严重股骨骨量丢失的嵌压植骨术：翻修全髋关节置换术的手术技术
JBJS Essent Surg Tech. 2022 Feb 16;12(1). doi: 10.2106/JBJS.ST.20.00043. eCollection 2022 Jan-Mar.
6
Atypical femur fractures among breast cancer and multiple myeloma patients receiving intravenous bisphosphonate therapy.接受静脉用双膦酸盐治疗的乳腺癌和多发性骨髓瘤患者中的非典型股骨骨折。
Bone. 2012 Sep;51(3):524-7. doi: 10.1016/j.bone.2012.05.010. Epub 2012 May 23.
7
Intraoperative fracture of the femur in revision total hip arthroplasty with a diaphyseal fitting stem.使用骨干适配型股骨柄进行翻修全髋关节置换术中的股骨术中骨折
J Bone Joint Surg Am. 2004 Mar;86(3):480-5. doi: 10.2106/00004623-200403000-00004.
8
Chemotherapy May Obviate Prophylactic Femoral Nail Surgery for Multiple Myeloma Patients With High Mirels' Score Lesions and Impending Pathological Hip Fracture.化疗可能使患有高米雷尔评分病变且即将发生病理性髋部骨折的多发性骨髓瘤患者无需进行预防性股骨钉手术。
Cureus. 2023 Apr 17;15(4):e37670. doi: 10.7759/cureus.37670. eCollection 2023 Apr.
9
Is a Cephalomedullary Nail Durable Treatment for Patients With Metastatic Peritrochanteric Disease?经股骨转子间骨折内固定治疗转移性股骨转子周围疾病的效果是否持久？
Clin Orthop Relat Res. 2018 Dec;476(12):2392-2401. doi: 10.1097/CORR.0000000000000523.
10
[Surgical technique and early clinical outcomes of direct anterior approach to total hip arthroplasty].[全髋关节置换术直接前路手术技术及早期临床疗效]
Beijing Da Xue Xue Bao Yi Xue Ban. 2017 Apr 18;49(2):206-213.

引用本文的文献

1
Atypical Presentation of Multiple Myeloma Affecting Appendicular Skeleton Associated with Pathological Neck of Femur and Proximal Humerus Fractures - A Case Report.多发性骨髓瘤累及四肢骨骼伴股骨颈和肱骨近端病理性骨折的非典型表现——病例报告
J Orthop Case Rep. 2024 Aug;14(8):174-178. doi: 10.13107/jocr.2024.v14.i08.4690.

本文引用的文献

1
Greater trochanter fixed with a claw plate and cable system in complex primary and revision total hip arthroplasty: long-term follow-up.复杂初次及翻修全髋关节置换术中使用爪板和缆索系统固定大转子：长期随访。
Int Orthop. 2022 Nov;46(11):2553-2560. doi: 10.1007/s00264-022-05538-3. Epub 2022 Aug 23.
2
Outcomes of press-fit uncemented versus cemented hip arthroplasty in the oncologic patient.肿瘤患者中压配式非骨水泥型与骨水泥型髋关节置换术的疗效
J Orthop. 2020 May 4;22:198-202. doi: 10.1016/j.jor.2020.04.022. eCollection 2020 Nov-Dec.
3
Fractures and survival in multiple myeloma: results from a population-based study.
多发性骨髓瘤的骨折与生存：一项基于人群的研究结果。
Haematologica. 2020 Apr;105(4):1067-1073. doi: 10.3324/haematol.2019.230011. Epub 2019 Dec 2.
4
Early Clinical and Economic Outcomes of Prophylactic and Acute Pathologic Fracture Treatment.预防性和急性病理性骨折治疗的早期临床和经济结果。
J Oncol Pract. 2019 Feb;15(2):e132-e140. doi: 10.1200/JOP.18.00431. Epub 2018 Dec 4.
5
Pathogenesis of bone disease in multiple myeloma: from bench to bedside.多发性骨髓瘤中骨病的发病机制：从基础到临床。
Blood Cancer J. 2018 Jan 12;8(1):7. doi: 10.1038/s41408-017-0037-4.
6
UNCEMENTED ARTHROPLASTY AFTER HIP METASTATIC DISEASE AND MULTIPLE MYELOMA.髋关节转移性疾病和多发性骨髓瘤后的非骨水泥型关节成形术
Acta Ortop Bras. 2016 Jul-Aug;24(4):191-195. doi: 10.1590/1413-785220162404158362.
7
Is It Appropriate to Treat Sarcoma Metastases With Intramedullary Nailing?使用髓内钉治疗肉瘤转移灶是否合适？
Clin Orthop Relat Res. 2017 Jan;475(1):212-217. doi: 10.1007/s11999-016-5069-8. Epub 2016 Nov 1.
8
The relationship between time to initiation of adjuvant chemotherapy and survival in breast cancer: a systematic review and meta-analysis.辅助化疗开始时间与乳腺癌生存率之间的关系：一项系统评价和荟萃分析。
Breast Cancer Res Treat. 2016 Nov;160(1):17-28. doi: 10.1007/s10549-016-3960-3. Epub 2016 Sep 8.
9
Surgical management of metastatic long bone fractures: principles and techniques.转移性长骨骨折的外科治疗：原则与技术。
J Am Acad Orthop Surg. 2014 Feb;22(2):90-100. doi: 10.5435/JAAOS-22-02-90.
10
Clinical impact of delaying initiation of adjuvant chemotherapy in patients with breast cancer.乳腺癌患者辅助化疗起始时间延迟的临床影响。
J Clin Oncol. 2014 Mar 10;32(8):735-44. doi: 10.1200/JCO.2013.49.7693. Epub 2014 Jan 27.