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骨科手术前肾细胞癌骨转移的栓塞治疗

Embolization of Renal Cell Carcinoma Skeletal Metastases Preceding Orthopedic Surgery.

作者信息

Amado Adam A, Chahrour Hussein, Hindi Hussam, Sankaran Priya, Harb Ali

机构信息

Interventional Radiology, Detroit Medical Center (DMC), Detroit, USA.

出版信息

Cureus. 2023 Apr 21;15(4):e37961. doi: 10.7759/cureus.37961. eCollection 2023 Apr.

Abstract

Renal cell carcinoma (RCC) is the most common type of renal malignancy in adults. Bone is a major site of metastatic disease from RCC. Osseous metastatic disease from RCC is often seen in the spine, pelvis, and femur, and is usually hypervascular in nature like its primary tumor source. This can cause significant pain, reduced function, pathological fracture, nerve compression, and decreased quality of life during cancer treatment and disease course. Surgical treatments for pathological fracture of the femur include resection, reconstruction, and stabilization with arthroplasty or placement of an intramedullary nail. This series looks at three cases of renal cell carcinoma metastases to the hip with pre-procedural embolization and orthopedic stabilization. Interventional radiology embolization of the arterial supply to the metastatic hypervascular bone lesions can reduce intraoperative blood loss and associated complications.

摘要

肾细胞癌(RCC)是成人中最常见的肾脏恶性肿瘤类型。骨是RCC转移性疾病的主要部位。RCC的骨转移性疾病常见于脊柱、骨盆和股骨,并且通常像其原发肿瘤来源一样本质上是高血供的。这会导致严重疼痛、功能减退、病理性骨折、神经受压,并在癌症治疗和病程中降低生活质量。股骨病理性骨折的手术治疗包括切除、重建以及通过关节成形术或髓内钉置入进行固定。本系列研究了三例肾细胞癌转移至髋部并进行术前栓塞和骨科固定的病例。对转移性高血供骨病变的动脉供应进行介入放射学栓塞可减少术中失血及相关并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884f/10200828/3bfd2477312f/cureus-0015-00000037961-i01.jpg

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