Saki Kourosh, Bahmani Mahmoud, Zamanian Golnaz, Abbasi Naser, Aidy Ali, Manouchehri Aliasghar, Mandal Sudip Kumar, Ganguly Paramita, Shokri Samira
Department of Psychiatry, School of Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Caspian J Intern Med. 2023 Spring;14(2):356-364. doi: 10.22088/cjim.14.2.356.
Every year, drug poisoning is the most prevalent reason for referring patients to medical centers. This study aimed to evaluation of morphine, methadone, digoxin, and dronabinol poisoning in Shahid Mostafa Khomeini Hospital in Ilam.
In this In this Cross-sectional study, patient samples suspected of morphine, methadone, digoxin, and dronabinol poisoning referred to the toxicology laboratory of Ilam University of Medical Sciences were analyzed using the HPLC method, and the results were analysed using SPSS software.
Results showed that the percentage of drug use is greater in men than in women. The highest percentage of morphine and methadone poisonings were detected in those under the age of 40, whereas the highest percentage of digoxin poisonings were recorded in those over the age of 80. As a result, the average age of digoxin users was substantially greater in men than in women. Methadone consumers showed significantly greater blood levels than others. In addition, there was a significant difference (P<0.01) in blood levels between men and women who used morphine.
In general, it is important to understand the status of drug poisoning with drugs such as morphine, methadone, digoxin, and dronabinol, as well as the prognosis associated with the treatment process of such poisoning.
每年,药物中毒都是患者前往医疗中心就诊的最常见原因。本研究旨在评估伊拉姆省沙希德·穆斯塔法·霍梅尼医院的吗啡、美沙酮、地高辛和屈大麻酚中毒情况。
在这项横断面研究中,对转诊至伊拉姆医科大学毒理学实验室的疑似吗啡、美沙酮、地高辛和屈大麻酚中毒的患者样本采用高效液相色谱法进行分析,并使用SPSS软件对结果进行分析。
结果显示,男性药物使用比例高于女性。吗啡和美沙酮中毒的最高比例出现在40岁以下人群中,而地高辛中毒的最高比例出现在80岁以上人群中。因此,男性地高辛使用者的平均年龄显著高于女性。美沙酮使用者的血液水平显著高于其他人。此外,使用吗啡的男性和女性之间的血液水平存在显著差异(P<0.01)。
总体而言,了解吗啡、美沙酮、地高辛和屈大麻酚等药物的中毒状况以及此类中毒治疗过程的预后情况非常重要。