• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

外耳道脂溢性角化病及其治疗

Seborrhoeic Keratosis of External Auditory Canal & its Management.

作者信息

Sahoo Anjan Kumar, Chakraborty Namrata, Bonthu Pavan Kumar

机构信息

Department of ENT and Head Neck Surgey, All India Institute oF Medical Sciences, BhopalMadhya Pradesh, India.

出版信息

Iran J Otorhinolaryngol. 2023 Mar;35(127):109-112. doi: 10.22038/IJORL.2023.67509.3307.

DOI:10.22038/IJORL.2023.67509.3307
PMID:37223401
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10202162/
Abstract

INTRODUCTION

Seborrhoeic keratosis (SK) is a benign neoplasm of the skin. They are usually found to occur anywhere in the body except palms, soles and mucous membranes. The skin of the external auditory canal is an extremely rare site for the occurrence of this benign neoplasm. Malignant transformation rarely occurs in this benign condition. It should be differentiated from other malignant condition like squamous cell carcinoma, basal cell carcinoma, Bowen's disease, malignant melanoma or keratoacanthoma. Surgery is the mainstay of treatment though recurrence is very common. It can be removed by cryotherapy using liquid nitrogen or curettage, light fulgaration, shave removal or painting with pure TCA if the lesion is small. Diathermy shoul be used as minimal as possible to avoid scar formation.

CASE REPORT

An elderly female presented to ENT OPD with left ear blood-stained discharge. On inspection there was irregular blackish mass filling the entire left external auditory canal, fine needle aspiration cytology came to be seborrhoeic keratosis. Since on imaging the tumor was confined to the external auditory canal, it was excised completely by transcanal route. Surprisingly histopathology came to be squamous cell carcinoma. Considering the age and limited confinement of the tumor, she was kept on regular follow up.

CONCLUSION

Seborrhoeic keratosis though a common benign tumor, malignant transformation may occur. Treatment is patient specific and may be modified considering the age and comorbidity of the patient.

摘要

引言

脂溢性角化病(SK)是一种皮肤良性肿瘤。它们通常见于身体任何部位,除了手掌、脚底和黏膜。外耳道皮肤是这种良性肿瘤极其罕见的发病部位。这种良性病变很少发生恶变。它应与其他恶性疾病如鳞状细胞癌、基底细胞癌、鲍温病、恶性黑色素瘤或角化棘皮瘤相鉴别。手术是主要的治疗方法,不过复发很常见。如果病变较小,可以通过液氮冷冻疗法、刮除术、轻度电灼、削除术或用纯三氯乙酸涂抹来去除。应尽量少用电凝术以避免形成瘢痕。

病例报告

一名老年女性因左耳血性分泌物就诊于耳鼻喉科门诊。检查发现整个左外耳道有不规则黑色肿物,细针穿刺细胞学检查结果为脂溢性角化病。由于影像学检查显示肿瘤局限于外耳道,遂通过经耳道途径将其完全切除。令人惊讶的是,组织病理学检查结果为鳞状细胞癌。考虑到患者年龄以及肿瘤局限的情况,对她进行定期随访。

结论

脂溢性角化病虽是一种常见的良性肿瘤,但可能发生恶变。治疗应因人而异,并可根据患者的年龄和合并症进行调整。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9320/10202162/d4b624f7c7ed/ijo-35-109-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9320/10202162/6eb8fb35cfdc/ijo-35-109-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9320/10202162/827f335bb8a4/ijo-35-109-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9320/10202162/c3c731db0e87/ijo-35-109-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9320/10202162/d4b624f7c7ed/ijo-35-109-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9320/10202162/6eb8fb35cfdc/ijo-35-109-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9320/10202162/827f335bb8a4/ijo-35-109-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9320/10202162/c3c731db0e87/ijo-35-109-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9320/10202162/d4b624f7c7ed/ijo-35-109-g004.jpg

相似文献

1
Seborrhoeic Keratosis of External Auditory Canal & its Management.外耳道脂溢性角化病及其治疗
Iran J Otorhinolaryngol. 2023 Mar;35(127):109-112. doi: 10.22038/IJORL.2023.67509.3307.
2
Inverted Follicular Keratosis: A Rare Presentation in External Ear Canal.倒置性毛囊角化病:外耳道的一种罕见表现。
Indian J Otolaryngol Head Neck Surg. 2024 Feb;76(1):1244-1246. doi: 10.1007/s12070-023-04241-y. Epub 2023 Oct 10.
3
Seborrheic Keratosis in the Auricle: A Rare Tumor.耳廓脂溢性角化病:一种罕见肿瘤
Ear Nose Throat J. 2019 Oct-Nov;98(9):560-561. doi: 10.1177/0145561319830069. Epub 2019 Feb 12.
4
Eccrine porocarcinoma and Bowen's disease arising in a seborrhoeic keratosis.脂溢性角化病中发生的小汗腺汗孔癌和鲍温病。
Clin Exp Dermatol. 2007 Jan;32(1):54-6. doi: 10.1111/j.1365-2230.2006.02260.x. Epub 2006 Sep 27.
5
Seborrhoeic keratosis or occult malignant neoplasm of the skin?脂溢性角化病还是隐匿性皮肤恶性肿瘤?
J Eur Acad Dermatol Venereol. 2002 Mar;16(2):168-70. doi: 10.1046/j.1468-3083.2002.00396.x.
6
[Actinic keratosis, Bowen's disease, keratoacanthoma and squamous cell carcinoma of the skin].[光化性角化病、鲍恩病、角化棘皮瘤和皮肤鳞状细胞癌]
Pathologe. 2015 Feb;36(1):16-29. doi: 10.1007/s00292-014-2063-3.
7
Activation of fibroblast growth factor receptor 3 and oncogene-induced senescence in skin tumours.皮肤肿瘤中纤维母细胞生长因子受体3的激活与癌基因诱导的衰老
Br J Dermatol. 2009 Jun;160(6):1258-63. doi: 10.1111/j.1365-2133.2009.09068.x. Epub 2009 Mar 9.
8
Seborrhoeic keratosis and malignancy: collision tumour or malignant transformation?脂溢性角化病与恶性肿瘤:碰撞瘤还是恶性转化?
Australas J Dermatol. 2006 May;47(2):106-8. doi: 10.1111/j.1440-0960.2006.00242.x.
9
Comparative histochemical study of Bowen's disease and actinic keratosis: preserved normal basal cells in Bowen's disease.鲍温病与光化性角化病的组织化学对比研究:鲍温病中基底细胞保持正常
Eur J Histochem. 2001;45(2):177-90. doi: 10.4081/1628.
10
Study of Clinicopathological Presentation and Management of Malignant Tumours of the Ear and Temporal Bone at Tertiary Care Cancer Hospital.三级护理癌症医院耳部及颞骨恶性肿瘤的临床病理表现及治疗研究
Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):3662-3670. doi: 10.1007/s12070-020-02346-2. Epub 2021 Jan 20.

引用本文的文献

1
Relapsing Irritated Seborrheic Keratosis of External Auditory Canal and its Management.外耳道复发性刺激性脂溢性角化病及其治疗
Indian J Otolaryngol Head Neck Surg. 2024 Feb;76(1):1272-1274. doi: 10.1007/s12070-023-04262-7. Epub 2023 Oct 13.

本文引用的文献

1
Differential Diagnosis of Seborrheic Keratosis: Clinical and Dermoscopic Features.脂溢性角化病的鉴别诊断:临床及皮肤镜特征
J Drugs Dermatol. 2017 Sep 1;16(9):835-842.
2
Squamous cell carcinomas in situ arising in seborrheic keratoses: an association with concomitant immunosuppression?脂溢性角化病中发生的原位鳞状细胞癌:与伴随的免疫抑制有关?
Int J Dermatol. 2014 Nov;53(11):1346-50. doi: 10.1111/ijd.12086. Epub 2014 Jun 5.
3
Seborrheic keratosis of the external auditory canal in a 1-year-old boy.
Turk J Pediatr. 2012 Sep-Oct;54(5):543-4.
4
Seborrheic keratosis of the external auditory canal.外耳道脂溢性角化病
Otol Neurotol. 2012 Sep;33(7):e61-2. doi: 10.1097/MAO.0b013e318254edb1.
5
Seborrheic keratosis of the external auditory canal.外耳道脂溢性角化病
Otol Neurotol. 2012 Jun;33(4):e27-8. doi: 10.1097/MAO.0b013e31823c916a.