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战地针刺疗法与酮咯酸治疗急诊科疼痛的对比研究

Battlefield Acupuncture vs Ketorolac for Treating Pain in the Emergency Department.

作者信息

Galka Eva, Elfessi Zane, Singh Tulika, Liu Erica, Turnbull Caitlin

机构信息

Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois.

University of Illinois at Chicago College of Pharmacy.

出版信息

Fed Pract. 2023 Apr;40(4):110-115. doi: 10.12788/fp.0369. Epub 2023 Apr 18.

Abstract

BACKGROUND

Many patients arrive in the emergency department (ED) with acute pain. Battlefield acupuncture (BFA) uses small, semipermanent acupuncture needles in 5 set points anatomically located on each ear to reduce pain in a few minutes. Pain relief can last months, depending on the pathology of the pain. At the Jesse Brown Veterans Affairs Medical Center (JBVAMC) ED, ketorolac 15 mg is the preferred first-line treatment of acute, noncancer pain. In 2018, BFA was offered first to veterans presenting with acute or acute-on-chronic pain to the ED; however, its effectiveness in pain reduction vs ketorolac has not been evaluated in this patient population. The objective of this study was to determine whether BFA monotherapy was noninferior to ketorolac 15 mg for reducing pain scores in the ED.

METHODS

This study was a retrospective, electronic chart review of patients who presented to JBVAMC ED with acute pain or acute-on-chronic pain and received ketorolac or BFA. The primary endpoint was the mean difference in the numeric rating scale (NRS) pain score from baseline. Secondary endpoints included the number of patients receiving pain medications, including topical analgesics, at discharge and treatment-related adverse events in the ED.

RESULTS

A total of 61 patients were included in the study. Baseline characteristics were similar between the 2 groups except for the average baseline NRS pain score, which was higher in the BFA group (8.7 vs 7.7; = .02). The mean difference in NRS pain scores from baseline to post-intervention was 3.9 for the BFA group and 5.1 for the ketorolac group. The difference in reducing the NRS pain score between the intervention groups was not statistically significant. No adverse events were observed in either treatment group.

CONCLUSIONS

For treating acute and acute-on-chronic pain in the ED, BFA did not differ compared with ketorolac 15 mg in NRS pain score reduction. This study's results add to the limited existing literature suggesting that both interventions could result in clinically significant reductions in pain scores for patients presenting to the ED with severe and very severe pain, indicating BFA could be a viable nonpharmacologic treatment option.

摘要

背景

许多患者因急性疼痛前来急诊科就诊。战地针刺疗法(BFA)使用细小的半永久性针灸针,分别刺入每只耳朵上解剖定位的5个穴位,在几分钟内减轻疼痛。根据疼痛的病理情况,疼痛缓解可持续数月。在杰西·布朗退伍军人事务医疗中心(JBVAMC)急诊科,15毫克酮咯酸是急性非癌性疼痛的首选一线治疗药物。2018年,BFA首先提供给急诊科出现急性或慢性疼痛急性发作的退伍军人;然而,在该患者群体中,与酮咯酸相比,其在减轻疼痛方面的有效性尚未得到评估。本研究的目的是确定BFA单药治疗在降低急诊科疼痛评分方面是否不劣于15毫克酮咯酸。

方法

本研究是一项回顾性电子病历审查,纳入了因急性疼痛或慢性疼痛急性发作到JBVAMC急诊科就诊并接受酮咯酸或BFA治疗的患者。主要终点是数字评分量表(NRS)疼痛评分相对于基线的平均差值。次要终点包括出院时接受止痛药物(包括局部镇痛药)治疗的患者数量以及急诊科与治疗相关的不良事件。

结果

本研究共纳入61例患者。两组的基线特征相似,但平均基线NRS疼痛评分除外,BFA组的平均基线NRS疼痛评分更高(8.7对7.7;P = 0.02)。BFA组从基线到干预后的NRS疼痛评分平均差值为3.9,酮咯酸组为5.1。两组间在降低NRS疼痛评分方面的差异无统计学意义。两个治疗组均未观察到不良事件。

结论

在急诊科治疗急性和慢性疼痛急性发作时,BFA在降低NRS疼痛评分方面与15毫克酮咯酸无差异。本研究结果补充了现有有限的文献,表明这两种干预措施均可使急诊科中重度和极重度疼痛患者的疼痛评分在临床上显著降低,这表明BFA可能是一种可行的非药物治疗选择。

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