Blenkinsopp W K, Clayton R J, Haffenden G P
J Clin Pathol. 1978 Dec;31(12):1143-6. doi: 10.1136/jcp.31.12.1143.
Cryostat sections of normal skin from 57 white adults were examined by direct and indirect immunofluorescence for immunoglobulins, complement factors, and transferrin. The results for basement membrane zone (BMX) were significantly different for the 11 face and 46 non-face biopsies: in the face, IgM was found in five, IgG in two, IgA in one, and C3 in none, whereas, in non-face, IgM was present in six, IgG in none, IgA in one, and C3 in five. The results for dermal vessel walls (DV) were not apparently different for face and non-face; in the 57 biopsies IgM was present in one, IgG in none, IgA in one, and C3 in one. The 11 biopsies from the face and 26 of the non-face biopsies were examined further. No IgD or C4 was identified, but one case (scalp) showed BMZ Clq, properdin, and transferrin, and in two cases (one face, one non-face) DV properdin was found. Cytoid bodies (IgM and IgA) were present in moderate numbers in one case; all other positive reactions were finely granular.
对57名白人成年人的正常皮肤冷冻切片进行了直接和间接免疫荧光检查，以检测免疫球蛋白、补体因子和转铁蛋白。11份面部活检和46份非面部活检的基底膜区（BMX）结果存在显著差异：在面部，5份样本中发现IgM，2份样本中发现IgG，1份样本中发现IgA，无样本中发现C3；而在非面部，6份样本中存在IgM，无样本中存在IgG，1份样本中存在IgA，5份样本中存在C3。面部和非面部的真皮血管壁（DV）结果无明显差异；在57份活检样本中，1份样本中存在IgM，无样本中存在IgG，1份样本中存在IgA，1份样本中存在C3。对11份面部活检样本和26份非面部活检样本进行了进一步检查。未发现IgD或C4，但1例（头皮）显示基底膜区Clq、备解素和转铁蛋白，2例（1例面部、1例非面部）发现真皮血管壁备解素。1例样本中存在中等数量的细胞样小体（IgM和IgA）；所有其他阳性反应均为细颗粒状。
