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[皮肤型红斑狼疮的直接免疫荧光检查]

[Direct immunofluorescence in cutaneous lupus erythematosus].

作者信息

Honeyman Mauro J F, Robles Velasco A

出版信息

Med Cutan Ibero Lat Am. 1976;4(1):41-4.

PMID:790052
Abstract

A study of the Direct Immunofluorescence Method in skin biopsies of 62 patients with discoid lupus erythematosus is presented. All the specimens were examined to determine the presence of immunoglobulins (IgG, IgM, IgA) and complement (C3) on the different histological structures of the skin. The presence of immunoglobulins and complement was detected not only in the basement membrane of the lesion but also on the hyaline bodies, collagen fibres, dermal capillaries, basal membrane of hair follicles, dermal inflammatory cells, sweat glands and arrector pili muscles. The significance of these findings is discussed.

摘要

本文介绍了对62例盘状红斑狼疮患者皮肤活检采用直接免疫荧光法的研究。对所有标本进行检查,以确定皮肤不同组织结构上免疫球蛋白(IgG、IgM、IgA)和补体(C3)的存在情况。不仅在病变的基底膜中检测到免疫球蛋白和补体,在透明小体、胶原纤维、真皮毛细血管、毛囊基底膜、真皮炎症细胞、汗腺和立毛肌中也检测到了。讨论了这些发现的意义。

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