Department of Respiratory Medicine, Yamagata Prefectual Central Hospital, Japan.
Division of Diagnostic Pathology, Saitama Cardiovascular and Respiratory Center, Japan.
Intern Med. 2024 Jan 15;63(2):277-282. doi: 10.2169/internalmedicine.1875-23. Epub 2023 May 24.
We herein report a case of polyclonal hyperglobulinemia with multiple pulmonary cysts and nodules. The histopathological findings allowed us to speculate about the mechanism underlying cyst formation in these pathological conditions, which has not yet been thoroughly elucidated. The patient was a 49-year-old woman who presented with multiple pulmonary multilocular cysts and nodules. A lung biopsy revealed features of nodular lymphoid hyperplasia. Notably, lung structure fragmentation was evident, suggesting that structural destruction may have accompanied the disease during its course. The cysts were considered to have formed due to destruction of the lung structures.
我们在此报告一例多发性肺囊肿和结节的多克隆高球蛋白血症。组织病理学发现使我们推测这些病理情况下囊肿形成的机制，而这尚未得到彻底阐明。患者为 49 岁女性，表现为多发性肺多房性囊肿和结节。肺活检显示结节性淋巴组织增生的特征。值得注意的是，肺部结构碎片明显，表明在疾病过程中可能伴随着结构破坏。这些囊肿被认为是由于肺部结构的破坏而形成的。
