Miyoshi Seigo, Hamada Hironobu, Katayama Hitoshi, Hamaguchi Naohiko, Irifune Kazunori, Ito Ryoji, Ohtsuki Yuji, Yoshino Tadashi, Higaki Jitsuo
Department of Integrated Medicine and Informatics, Ehime University Graduate School of Medicine, Toon.
Intern Med. 2010;49(15):1617-21. doi: 10.2169/internalmedicine.49.3487. Epub 2010 Aug 2.
A 50-year-old man was admitted to our hospital for examination of an abnormal shadow on chest radiography. Computed tomography revealed multiple small nodular shadows in bilateral lung fields, with cavitation in a right S3 lesion that was resected by video-assisted thoracoscopic surgery. Histopathological examination revealed marked proliferation of lymphoid tissue, including many plasma cells that were polyclonal in nature. This case was considered to be pulmonary nodular lymphoid hyperplasia (PNLH). Several residual nodules spontaneously disappeared during the 6 years of follow-up. This was a rare case of PNLH with a resected cavity, followed by spontaneous regression of the remaining lesions.
一名50岁男性因胸部X线检查发现异常阴影而入院。计算机断层扫描显示双肺野有多个小结节阴影，右肺上叶前段（S3）病变有空洞形成，遂通过电视辅助胸腔镜手术切除。组织病理学检查显示淋巴组织显著增生，包括许多本质上为多克隆性的浆细胞。该病例被诊断为肺结节性淋巴组织增生（PNLH）。在6年的随访期间，几个残留结节自行消失。这是一例罕见的PNLH病例，有切除的空洞，随后其余病变自行消退。
