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感染后 2 年出现新发慢性疼痛的新冠后患者:横断面研究。

Post-COVID Patients With New-Onset Chronic Pain 2 Years After Infection: Cross-Sectional Study.

机构信息

From the Physiotherapy Department, Faculty of Health Sciences, University of Granada, Granada, Spain.

From the Physiotherapy Department, Faculty of Health Sciences, University of Granada, Granada, Spain.

出版信息

Pain Manag Nurs. 2023 Oct;24(5):528-534. doi: 10.1016/j.pmn.2023.04.010. Epub 2023 May 22.

Abstract

BACKGROUND

Although pain is common in non-hospitalized post-COVID-19 syndrome, only a few studies have provided information on the pain experience of these patients.

AIM

To identify the clinical and psychosocial profile associated with pain in non-hospitalized patients with post-COVID-19 syndrome.

METHOD

In this study there were three groups: healthy control group, successfully recovered group, and post-COVID syndrome group. Pain-related clinical profile and pain-related psychosocial variables were collected. Pain-related clinical profile included: pain intensity and interference (Brief Pain Inventory), central sensitization (Central Sensitization Scale), insomnia severity (Insomnia Severity Index), and pain treatment. Pain-related psychosocial variables were: fear of movement and (re)injury (Tampa Scale for Kinesiophobia), catastrophizing (Pain Catastrophizing Scale), depression, anxiety and stress (Depression, Anxiety and Stress Scale), and fear-avoidance beliefs (Fear Avoidance Beliefs Questionnaire).

RESULTS

In all, 170 participants were included in the study (healthy control group n = 58, successfully recovered group n = 57, and post-COVID syndrome group n = 55). Post-COVID syndrome group obtained significantly worse punctuation in pain-related clinical profile and psychosocial variables than the other two groups (p < .05).

CONCLUSIONS

In conclusion, patients with post-COVID-19 syndrome have experienced high pain intensity and interference, central sensitization, increased insomnia severity, fear of movement, catastrophizing, fear-avoidance beliefs, depression, anxiety, and stress.

摘要

背景

虽然非住院的新冠后综合征患者常伴有疼痛,但仅有少数研究提供了这些患者疼痛体验的相关信息。

目的

确定与非住院新冠后综合征患者疼痛相关的临床和心理社会特征。

方法

本研究有三组:健康对照组、成功康复组和新冠后综合征组。收集与疼痛相关的临床特征和心理社会变量。与疼痛相关的临床特征包括:疼痛强度和干扰(简明疼痛量表)、中枢敏化(中枢敏化量表)、失眠严重程度(失眠严重程度指数)和疼痛治疗。与疼痛相关的心理社会变量包括:运动恐惧和(再)损伤(运动恐惧量表)、灾难化(疼痛灾难化量表)、抑郁、焦虑和压力(抑郁、焦虑和压力量表)以及恐惧回避信念(恐惧回避信念问卷)。

结果

共纳入 170 名参与者(健康对照组 n=58 例,成功康复组 n=57 例,新冠后综合征组 n=55 例)。与其他两组相比,新冠后综合征组在与疼痛相关的临床特征和心理社会变量方面的评分明显更差(p<0.05)。

结论

总之,新冠后综合征患者经历了较高的疼痛强度和干扰、中枢敏化、增加的失眠严重程度、运动恐惧、灾难化、恐惧回避信念、抑郁、焦虑和压力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/810d/10201348/a8ff6333357e/gr1_lrg.jpg

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