Hock J
J Clin Periodontol. 1979 Feb;6(1):37-44. doi: 10.1111/j.1600-051x.1979.tb02289.x.
The objective of this study was to determine if the regular vascular network previously reported as occurring in noninflamed marginal gingiva would become re-established following plaque control and treatment of gingiva by gingivectomy and scaling. Gingivectomies were performed on dogs with and without pre-experimental gingivitis in order to obtain gingival specimens healed for 4, 8 and 12 weeks. Plaque was controlled using toothbrushing and topical applications of 0.2% chlorhexidine gluconate. After 12 weeks, the animals were perfused via the carotid arteries with glutaraldehyde and Microfil latex compound. Specimens were processed for either routine histology or examination of vascular morphology in methyl salicylate cleared tissues. The absence of inflammation in healed gingiva was evaluated clinically, using the Gingival and Plaque Indices, and histologically. Results showed that in healed clinically and histologically noninflamed gingiva, the vascular morphology was established as a series of looped vessels which could readily be distinguished from the regular network of vessels described by Hock (1975) in marginal gingiva that had neither been inflamed nor resected.
本研究的目的是确定先前报道的非炎症性边缘龈中出现的规则血管网络在菌斑控制以及通过牙龈切除术和洁治术治疗牙龈后是否会重新建立。对有和没有实验前牙龈炎的犬进行牙龈切除术，以获取愈合4周、8周和12周的牙龈标本。使用牙刷和局部应用0.2%葡萄糖酸氯己定来控制菌斑。12周后，通过颈动脉用戊二醛和Microfil乳胶复合物对动物进行灌注。标本进行常规组织学处理或在水杨酸甲酯透明组织中检查血管形态。使用牙龈指数和菌斑指数从临床和组织学上评估愈合牙龈中炎症的不存在情况。结果显示，在临床和组织学上愈合的非炎症性牙龈中，血管形态呈现为一系列环状血管，这很容易与Hock（1975年）描述的边缘龈中既未发炎也未切除的规则血管网络区分开来。
