Pengpid Supa, Peltzer Karl, Anantanasuwong Dararatt
Department of Health Education and Behavioral Sciences, Faculty of Public Health, Mahidol University, Bangkok, Thailand; Department of Public Health, Sefako Makgatho Health Sciences University, Pretoria, South Africa; and Department of Healthcare Administration, College of Medical and Health Science, Asia University, Taichung, Taiwan.
Department of Health Education and Behavioral Sciences, Faculty of Public Health, Mahidol University, Bangkok, Thailand; Department of Psychology, University of the Free State, Bloemfontein, South Africa; and Department of Psychology, College of Medical and Health Science, Asia University, Taichung, Taiwan.
BJPsych Open. 2023 May 25;9(3):e99. doi: 10.1192/bjo.2023.72.
There are no longitudinal studies investigating determinants of incident and persistent depressive symptoms in Southeast Asia.
To estimate the proportion and correlates of incident and persistent depressive symptoms in a prospective cohort study among middle-aged and older adults (≥45 years) in Thailand.
We analysed longitudinal data from the Health, Aging, and Retirement in Thailand (HART) surveys in 2015 and 2017. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression Scale. Logistic regression was used to calculate predictors of incident and persistent depressive symptoms.
In total, 290 of 4528 participants without depressive symptoms in 2015 had incident depressive symptoms in 2017 (9.8%) and 76 of 640 adults had persistent depressive symptoms (in both 2015 and 2017) (18.3%). In adjusted logistic regression analysis, having diabetes (adjusted odds ratio AOR = 1.48, 95% CI 1.07-2.05), musculoskeletal conditions (AOR = 1.56, 95% CI 1.01-2.41) and having three or more chronic conditions (AOR = 2.55, 95% CI 1.67-3.90) were positively associated and higher subjective economic status (AOR = 0.47, 95% CI 0.31-0.72) and social participation (AOR = 0.66, 95% CI 0.49-0.90) were inversely associated with incident depressive symptoms. Having a cardiovascular disease (AOR = 1.55, 95% CI 1.01-2.39) and having three or more chronic conditions (AOR = 2.47, 95% CI 1.07-5.67) were positively associated and social participation (AOR = 0.48, 95% CI 0.26-0.87) was inversely associated with persistent depressive symptoms.
One in ten middle-aged and older adults had incident depressive symptoms at 2-year follow-up. The prevalence of incident and/or persistent depression was higher in people with a lower subjective economic status, low social participation, diabetes, musculoskeletal disorders, cardiovascular conditions and a higher number of chronic diseases.
在东南亚地区，尚无纵向研究调查新发和持续存在的抑郁症状的决定因素。
在泰国一项针对中年及老年成年人（≥45岁）的前瞻性队列研究中，估计新发和持续存在的抑郁症状的比例及其相关因素。
我们分析了2015年和2017年泰国健康、老龄化与退休调查（HART）的纵向数据。使用流行病学研究中心抑郁量表评估抑郁症状。采用逻辑回归分析来计算新发和持续存在的抑郁症状的预测因素。
2015年无抑郁症状的4528名参与者中，共有290人在2017年出现新发抑郁症状（9.8%），640名成年人中有76人持续存在抑郁症状（2015年和2017年都有）（18.3%）。在调整后的逻辑回归分析中，患有糖尿病（调整后的优势比AOR = 1.48，95%置信区间CI 1.07 - 2.05）、肌肉骨骼疾病（AOR = 1.56，95% CI 1.01 - 2.41）以及患有三种或更多慢性疾病（AOR = 2.55，95% CI 1.67 - 3.90）与新发抑郁症状呈正相关，而较高的主观经济状况（AOR = 0.47，95% CI 从0.31至0.72）和社会参与度（AOR = 0.66，95% CI 0.49 - 0.90）与新发抑郁症状呈负相关。患有心血管疾病（AOR = 1.55，95% CI 1.01 - 2.39）以及患有三种或更多慢性疾病（AOR = 2.47，95% CI 1.07 - 5.67）与持续存在的抑郁症状呈正相关，而社会参与度（AOR = 0.48，95% CI 0.26 - 0.87）与持续存在的抑郁症状呈负相关。
在为期两年的随访中，每十名中年及老年成年人中有一人出现新发抑郁症状。主观经济状况较低、社会参与度低、患有糖尿病、肌肉骨骼疾病、心血管疾病以及患有更多慢性疾病的人群中，新发和/或持续存在抑郁症状的患病率更高。
