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基于正念认知疗法治疗慢性非癌症疼痛和处方阿片类药物使用障碍:一项定性试点研究,评估其可行性和感知变化过程。

Mindfulness-based cognitive therapy for chronic noncancer pain and prescription opioid use disorder: A qualitative pilot study of its feasibility and the perceived process of change.

机构信息

Department of Psychiatry, Radboud University Medical Center, Nijmegen, The Netherlands.

Nijmegen Institute for Scientist-Practitioners in Addiction (NISPA), Nijmegen, The Netherlands.

出版信息

Brain Behav. 2023 Jul;13(7):e3005. doi: 10.1002/brb3.3005. Epub 2023 May 24.

DOI:10.1002/brb3.3005
PMID:37226589
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10338789/
Abstract

BACKGROUND

Mindfulness-based interventions have a positive impact on pain, craving, and well-being in both patients with chronic pain and those with opioid use disorder (OUD). Although data are limited, mindfulness-based cognitive therapy (MBCT) might be a promising treatment for patients with chronic noncancer pain combined with OUD. The aim of this qualitative study was to explore the feasibility and process of change during MBCT in this particular population.

METHODS

In this qualitative pilot study, 21 patients who were hospitalized for rotation to buprenorphine/naloxone as agonist treatment for chronic pain and OUD were offered MBCT. Semistructured interviews were conducted to explore experienced barriers and facilitators to MBCT. Patients who participated in MBCT were also interviewed on their perceived process of change.

RESULTS

Of 21 patients invited to participate in MBCT, 12 initially expressed interest but only four eventually participated in MBCT. The timing of the intervention, group format, somatic complaints, and practical difficulties were identified as the main barriers to participation. Facilitating factors included having a positive attribution toward MBCT, an intrinsic motivation to change, and practical support. The four MBCT participants mentioned several important mechanisms of change, including reduction of opioid craving and improved coping with pain.

CONCLUSIONS

MBCT offered in the current study was not feasible for the majority of patients with pain and OUD. Changing the timing of MBCT by providing it at an earlier stage of the treatment and offering MBCT in an online format may facilitate participation.

摘要

背景

正念干预对慢性疼痛患者和阿片类药物使用障碍(OUD)患者的疼痛、渴望和幸福感都有积极影响。尽管数据有限,但正念认知疗法(MBCT)可能是治疗慢性非癌痛合并 OUD 的一种有前途的方法。本定性研究的目的是探讨在该特定人群中进行 MBCT 的可行性和变化过程。

方法

在这项定性试点研究中,21 名因慢性疼痛和 OUD 而住院接受丁丙诺啡/纳洛酮作为阿片类激动剂治疗的患者被提供了 MBCT。进行半结构化访谈,以探讨 MBCT 面临的经验障碍和促进因素。参加 MBCT 的患者还就他们感知的变化过程进行了访谈。

结果

在被邀请参加 MBCT 的 21 名患者中,有 12 名最初表示有兴趣,但只有 4 名最终参加了 MBCT。干预的时间、小组形式、躯体抱怨和实际困难被确定为参与的主要障碍。促进因素包括对 MBCT 的积极归因、改变的内在动机和实际支持。4 名参加 MBCT 的患者提到了几个重要的变化机制,包括减少阿片类药物的渴望和改善对疼痛的应对。

结论

在本研究中提供的 MBCT 对大多数患有疼痛和 OUD 的患者来说是不可行的。通过在治疗的早期阶段提供 MBCT 并提供在线格式的 MBCT,可以改变 MBCT 的时间,从而促进参与。