Aubriot F X, Dubuisson J B, Henrion R
J Gynecol Obstet Biol Reprod (Paris). 1986;15(2):141-6.
Genital infections and in particular sexually transmitted diseases are mainly responsible for tubal sterility. We have studied five factors each of which could carry responsibility for this sterility. All were in some degree associated with infection in the 588 patients who were operated on for tuboplasty and 69 patients who had in vitro fertilisation. There results have been compared with 50 sterile women who had healthy tubes and with 8,356 women who were delivered during the same period of time. The previous histories of women who had extra-uterine pregnancies were significantly more frequent for these infections in the tubes leading to chronic salpingitis. Acute salpingitis was given in the history in about 35% of women who had to have tubal surgery or in vitro fertilisation. This was significantly higher than those sterile women who had healthy tubes and those who were delivered of babies. There was a significantly raised number of those where the serology was positive for chlamydia trachomatis in sterile women with tubal lesions. We have also been able to note that there was correlation between the frequency with which positive serology was found and the degree of severity of the tubal lesions. So, the serology was often positive in cases of hydrosalpinx (77.3%) and in double lesions (91.5%). These figures were significantly higher than those who had proximal blocks (61%) and who had adhesions (54.8%). The frequency of therapeutic terminations of pregnancy in patients with tubal lesions was significantly higher than those in the control groups.(ABSTRACT TRUNCATED AT 250 WORDS)
生殖器感染,尤其是性传播疾病,是输卵管性不孕的主要原因。我们研究了五个可能导致这种不孕的因素。在588例行输卵管成形术的患者和69例行体外受精的患者中,所有因素在某种程度上都与感染有关。将这些结果与50名输卵管健康的不孕女性以及同期分娩的8356名女性进行了比较。宫外孕女性的既往病史显示,这些导致慢性输卵管炎的感染在输卵管中更为常见。在约35%需要进行输卵管手术或体外受精的女性病史中,有急性输卵管炎。这一比例显著高于输卵管健康的不孕女性和已分娩的女性。在有输卵管病变的不孕女性中,沙眼衣原体血清学呈阳性的人数显著增加。我们还注意到,血清学阳性的频率与输卵管病变的严重程度之间存在相关性。因此,在输卵管积水(77.3%)和双重病变(91.5%)的病例中,血清学常常呈阳性。这些数字显著高于近端阻塞(61%)和粘连(54.8%)的患者。输卵管病变患者的治疗性终止妊娠频率显著高于对照组。(摘要截取自250字)