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输卵管炎和输卵管性不育病例腹腔镜拭子的微生物学研究。沙眼衣原体和支原体检测(作者译)

[A microbiological study of swabs taken laparoscopically in cases of salpingitis and tubal sterility. Research for Chlamydia trachomatis and for mycoplasmas (author's transl)].

作者信息

Henry-Suchet J, Catalan F, Loffredo V, Serfaty D, Piboulet A, Perol Y, Sanson M J, Debache C, Pigeau F, Coppin R, de Brux J, Paynard T

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1980;9(4):445-53.

PMID:6450231
Abstract

Research was made for chlamydia trachomatis and ureaplasma urealyticum in the peritoneum and the tubes of 99 women divided into 4 groups: 17 of them were being investigated because of acute salpingitis (Group A), 17 were being investigated for tubal sterility with chronic inflammation diagnosed laparoscopically (Group B), 29 were being investigated for tubal sterility without any laparoscopic evidence of inflammation (Group C) and 36 women had absolutely normal pelves and were being investigated for sterility. These were the control group (D). Swabs were also taken from the lower genital tracts as well as serological tests for chlamydia trachomatis and cytological samplings of the fluid from the Pouch of Douglas and the histology of the tubes. In the 17 women who had acute salpingitis the swabs 4 cases of C.T. and 4 of U.U. In the 46 women who had tubal sterility the laparoscopic swabs showed cases of C.T. and 7 of U.U. The swabs were most often positive in Group B. This group is characterised by a special appearence of the inflammation, with fluid present and viscous adhesions as well as peritoneal inflammatory cysts. These altogether help to make a presumptive diagnosis of C.T. infection on laparoscopy. In the control group of 36 cases there was no sign of C.T. in any case, although 2 swabs from the peritoneum showed U.U. So there is a statistically significant difference between the groups that were suspicious and the control group whether the results were obtained by cultures or by serological diagnosis. On the other hand there is no definitive difference as far as U.U. is concerned. These observations, which are similar to those published by other authors, lead us to think that micro-organisms and especially chlamydia trachomatis could be the bacteriological agent responsible for chronic inflammatory states found so frequently in women with tubal sterility.

摘要

对99名女性的腹膜和输卵管进行了沙眼衣原体和解脲脲原体的研究,这些女性被分为4组:其中17名因急性输卵管炎接受调查(A组),17名因腹腔镜诊断为慢性炎症的输卵管性不孕接受调查(B组),29名因无腹腔镜炎症证据的输卵管性不孕接受调查(C组),36名女性盆腔完全正常且因不孕接受调查,这些为对照组(D组)。还从下生殖道采集了拭子,进行了沙眼衣原体的血清学检测以及Douglas陷凹液的细胞学采样和输卵管组织学检查。在17名患有急性输卵管炎的女性中,拭子检测出4例沙眼衣原体和4例解脲脲原体。在46名患有输卵管性不孕的女性中,腹腔镜拭子检测出沙眼衣原体病例和7例解脲脲原体。拭子在B组中最常呈阳性。该组的炎症具有特殊表现,有液体存在、粘性粘连以及腹膜炎性囊肿。这些共同有助于在腹腔镜检查时作出沙眼衣原体感染的推测性诊断。在36例的对照组中,无论如何都没有沙眼衣原体的迹象,尽管从腹膜采集的2份拭子显示了解脲脲原体。因此,无论是通过培养还是血清学诊断获得结果,可疑组与对照组之间在统计学上都存在显著差异。另一方面,就解脲脲原体而言,没有明确差异。这些观察结果与其他作者发表的结果相似,使我们认为微生物尤其是沙眼衣原体可能是导致输卵管性不孕女性中频繁发现的慢性炎症状态的细菌病原体。

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