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空肠弯曲菌血症是低丙种球蛋白血症患者反复发热的一个原因。

Campylobacter jejuni bacteraemia as a cause of recurrent fever in a patient with hypogammaglobulinaemia.

作者信息

van der Meer J W, Mouton R P, Daha M R, Schuurman R K

出版信息

J Infect. 1986 May;12(3):235-9. doi: 10.1016/s0163-4453(86)94190-3.

DOI:10.1016/s0163-4453(86)94190-3
PMID:3722839
Abstract

In a hypogammaglobulinaemic patient with faecal cultures persistently positive for Campylobacter jejuni it was shown that C. jejuni bacteraemia was responsible for a long history of self-limiting attacks of fever. A focus of infection outside the gastro-intestinal tract was not found. Antimicrobial treatment failed to eradicate C. jejuni. Antibodies against C. jejuni were not detectable and there was also a defect in serum bactericidal activity. In contrast with normal serum, it was shown that, when patient's serum was used in tests, IgG and the components of complement C3 and C4 did not bind to C. jejuni.

摘要

在一名低丙种球蛋白血症患者中,其粪便培养持续显示空肠弯曲菌阳性,结果表明空肠弯曲菌血症是长期自限性发热发作的原因。未发现胃肠道外的感染病灶。抗菌治疗未能根除空肠弯曲菌。未检测到针对空肠弯曲菌的抗体,血清杀菌活性也存在缺陷。与正常血清相比,当使用患者血清进行检测时发现,IgG以及补体C3和C4的成分均不与空肠弯曲菌结合。

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Clin Microbiol Rev. 1998 Jul;11(3):440-9. doi: 10.1128/CMR.11.3.440.
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Erysipelas-like skin lesions associated with Campylobacter jejuni septicemia in patients with hypogammaglobulinemia.低丙种球蛋白血症患者空肠弯曲菌败血症相关的丹毒样皮肤病变
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