Gaschignard Margaux, Beaufils Fabien, Gallet Pauline, Clouzeau Haude, Menard Joris, Costanzo Aurélie, Nouard Lucie, Delhaes Laurence, Tetard Candice, Lamireau Thierry, Fayon Michael, Bui Stéphanie, Enaud Raphaël
Pediatric Cystic Fibrosis Reference Center (CRCM), Bordeaux University Hospital, Hôpital Pellegrin-Enfants, Centre d'Investigation Clinique (CIC 1401), Bordeaux, France.
Centre de Recherche Cardio-Thoracique de Bordeaux, Bordeaux University, INSERM U1045, U1045, Bordeaux, France.
Front Pediatr. 2023 May 9;11:1130792. doi: 10.3389/fped.2023.1130792. eCollection 2023.
Malnutrition is both a feature and major cause of morbidity in cystic fibrosis (CF). Therefore, nutritional management is an essential element of patient care. In 2016, an international guideline for nutritional management in patients with CF was published. In light of these recommendations, the aim of this study was to investigate the dietary intake of children with CF at the University Hospital of Bordeaux.
We conducted a retrospective study at the Paediatric CF Centre of the University Hospital of Bordeaux. Patients aged 2-18 years with CF who completed a 3-day food diary at home between January 2015 and December 2020 were included.
A total of 130 patients, with a median age of 11.8 [interquartile range (IQR): 8.3; 13.4] years, were included. The median Z-score for BMI was -0.35 (IQR: -0.9; 0.2) and 20% of the patients had a -score for BMI < -1. Recommended total energy intakes were achieved in 53% of the patients, particularly those with nutritional support. Recommended protein intake was met in 28% of the cases, while fat and carbohydrate intakes were met in 54%. Vitamin and micronutrient levels were normal in 80% of the patients, with the exception of vitamin K, which was within the therapeutic range in only 42% of the cases.
Recommended nutritional targets are difficult to achieve in patients with CF, and providing nutritional support during follow-up remains a challenge.
营养不良既是囊性纤维化（CF）的一个特征，也是发病的主要原因。因此，营养管理是患者护理的重要组成部分。2016年，发布了一份关于CF患者营养管理的国际指南。鉴于这些建议，本研究的目的是调查波尔多大学医院CF患儿的饮食摄入量。
我们在波尔多大学医院儿科CF中心进行了一项回顾性研究。纳入了2015年1月至2020年12月期间在家中完成了3天食物日记的2至18岁CF患者。
共纳入130例患者，中位年龄为11.8岁[四分位间距（IQR）：8.3；13.4]。BMI的中位Z评分为-0.35（IQR：-0.9；0.2），20%的患者BMI的Z评分< -1。53%的患者达到了推荐的总能量摄入量，尤其是那些接受营养支持的患者。28%的病例达到了推荐的蛋白质摄入量，而脂肪和碳水化合物摄入量达到的比例为54%。80%的患者维生素和微量营养素水平正常，但维生素K除外，仅42%的病例其维生素K水平在治疗范围内。
CF患者难以实现推荐的营养目标，在随访期间提供营养支持仍然是一项挑战。
