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一例免疫功能低下患者因摄入益生菌引发干酪乳杆菌心内膜炎的病例

A Case of Lactobacillus casei Endocarditis Associated With Probiotic Intake in an Immunocompromised Patient.

作者信息

Rahman Ali, Alqaisi Sura, Nath Jayant

机构信息

Internal Medicine, Mather Hospital/Northwell Health, Port Jefferson, USA.

Internal Medicine, Memorial Hospital Pembroke, Pembroke Pines, USA.

出版信息

Cureus. 2023 Apr 24;15(4):e38049. doi: 10.7759/cureus.38049. eCollection 2023 Apr.

DOI:10.7759/cureus.38049
PMID:37228522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10207843/
Abstract

Probiotics are microorganisms, typically bacteria, similar to beneficial microbiota found in the human gut, usually consumed as dietary supplements or fermented foods. Although probiotics are generally safe, several cases of bacteremia, sepsis, and endocarditis associated with probiotics have been reported. Here we report a rare case of endocarditis in a 71-year-old female, immunocompromised due to chronic steroid intake, who presented with a productive cough and low-grade fever. Blood cultures grew resistant to vancomycin and meropenem. Transesophageal echocardiography showed mitral and aortic vegetations; valve replacement was done after successfully removing vegetations. She was treated with a six-week course of daptomycin and recovered.

摘要

益生菌是微生物,通常为细菌,类似于人体肠道中发现的有益微生物群,通常作为膳食补充剂或发酵食品食用。尽管益生菌一般是安全的,但已有几例与益生菌相关的菌血症、败血症和心内膜炎的报道。在此,我们报告一例罕见的心内膜炎病例,患者为一名71岁女性,因长期服用类固醇而免疫功能低下,表现为咳痰和低热。血培养结果显示对万古霉素和美罗培南耐药。经食管超声心动图显示二尖瓣和主动脉瓣有赘生物;在成功清除赘生物后进行了瓣膜置换。她接受了为期六周的达托霉素治疗并康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ae/10207843/4fc3de991bdf/cureus-0015-00000038049-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ae/10207843/df41e5dbde37/cureus-0015-00000038049-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ae/10207843/e40fc2d4bf09/cureus-0015-00000038049-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ae/10207843/350ca4ff8bb2/cureus-0015-00000038049-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ae/10207843/4fc3de991bdf/cureus-0015-00000038049-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ae/10207843/df41e5dbde37/cureus-0015-00000038049-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ae/10207843/e40fc2d4bf09/cureus-0015-00000038049-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ae/10207843/350ca4ff8bb2/cureus-0015-00000038049-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84ae/10207843/4fc3de991bdf/cureus-0015-00000038049-i04.jpg

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2
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Cochrane Database Syst Rev. 2017 Dec 19;12(12):CD006095. doi: 10.1002/14651858.CD006095.pub4.
3
Timely Use of Probiotics in Hospitalized Adults Prevents Clostridium difficile Infection: A Systematic Review With Meta-Regression Analysis.
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Int J Mol Sci. 2024 Aug 6;25(16):8564. doi: 10.3390/ijms25168564.
4
Recent Records on Bacterial Opportunistic Infections via the Dietary Route.近期关于经饮食途径的细菌机会性感染的记录。
Microorganisms. 2023 Dec 29;12(1):69. doi: 10.3390/microorganisms12010069.
5
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6
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及时使用益生菌可预防住院成人艰难梭菌感染:系统评价与荟萃回归分析。
Gastroenterology. 2017 Jun;152(8):1889-1900.e9. doi: 10.1053/j.gastro.2017.02.003. Epub 2017 Feb 10.
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