Nwaobi Samuel, Khan Ayesha, Ojemolon Pius E, Ugoh Amaka C, Iheme Blessing C
Family Medicine, Piedmont Columbus Regional-Midtown, Columbus, USA.
Internal Medicine, Edward Via College of Osteopathic Medicine, Auburn, USA.
Cureus. 2023 Apr 23;15(4):e38028. doi: 10.7759/cureus.38028. eCollection 2023 Apr.
Acute pancreatitis (AP) is the painful inflammation of the pancreas. It is commonly associated with gallstones, excessive alcohol use, and certain medications. We report a case of hypertriglyceridemia-induced pancreatitis in a 35-year-old African American male with a history of alcohol abuse, tobacco use, and hyperlipidemia who presented with abdominal pain and intractable vomiting. During history taking, he reported chronic alcohol abuse over the past 10 years. On physical examination, he was ill-looking, with a dry mucous membrane and reproducible epigastric tenderness. Laboratory testing indicated markedly elevated triglycerides and lipase levels. Computed Tomography imaging showed signs of pancreatic inflammation. He was treated with aggressive intravenous fluid hydration, insulin infusion, and pain control medications. He demonstrated significant improvement and then transitioned to oral fibrates. Community resources for alcohol abuse treatment were provided and a referral was made to endocrinology for outpatient follow-up. This case highlights acute pancreatitis in a person with high alcohol use with elevated triglyceride and explores possible associations between these three.
急性胰腺炎(AP)是胰腺的疼痛性炎症。它通常与胆结石、过量饮酒和某些药物有关。我们报告一例35岁非裔美国男性因高甘油三酯血症诱发的胰腺炎,该患者有酗酒、吸烟和高脂血症病史,表现为腹痛和顽固性呕吐。在病史采集过程中,他报告过去10年有慢性酗酒史。体格检查时,他看起来病恹恹的,黏膜干燥,上腹部有压痛。实验室检查显示甘油三酯和脂肪酶水平显著升高。计算机断层扫描成像显示胰腺有炎症迹象。他接受了积极的静脉补液、胰岛素输注和止痛药物治疗。他病情明显好转,随后改用口服贝特类药物。提供了酗酒治疗的社区资源,并转诊至内分泌科进行门诊随访。本病例突出了高酒精摄入且甘油三酯升高患者的急性胰腺炎,并探讨了这三者之间可能的关联。