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乳腺癌幸存者的生活质量:保乳手术与全乳切除术(有无即刻乳房重建)的比较:一项前瞻性队列研究

Quality of life of breast cancer survivors: a comparison of breast conserving surgery versus total mastectomy with and without immediate reconstruction: a prospective cohort study.

作者信息

Vohra Lubna M, Javed Saad Malik, Jabeen Dua, Abidi Syeda Sakina, Tahseen Muhammad Umair

机构信息

Departments of Breast Surgery.

Surgery, Aga Khan University Hospital.

出版信息

Ann Med Surg (Lond). 2023 Apr 13;85(5):1513-1517. doi: 10.1097/MS9.0000000000000607. eCollection 2023 May.

Abstract

UNLABELLED

Quality of life after breast cancer surgery is frequently ignored during and after treatment in many cancer survivors. To enhance this aspect of patient's life should be the primary goal of every cancer treatment. Therefore, the present study aimed to highlight the quality of life and patients' satisfaction with their breast cosmesis following breast conserving surgery (BCS), total mastectomy with and without reconstruction.

MATERIAL AND METHODS

Data were collected prospectively from cancer patients who had undergone breast surgery at our institution from 1 January 2015 to 31 December 2021. The validated Breast-Q questionnaires were utilized for conducting patient interviews and mean scores between three cohorts were compared using one-way ANOVA test / Kruskal-Wallis test.

RESULTS

Overall, 210 patients were recruited in which 70 patients (33.3%) had undergone BCS, 71 patients (33.8%) had total mastectomy only and 69 (32.9%) patients had total mastectomy with reconstruction. Physical well-being scores were consistent between the three groups while patients operated with total mastectomy with reconstructive surgery scored higher in sexual and psychosocial health measures as compared to patients of total mastectomy. However, BCS patients were the most satisfied with their cosmetic outcome following patients of total mastectomy with reconstruction and without reconstruction.

CONCLUSION

Reconstruction postmastectomy has a positive impact on sexual and psychosocial well-being of survivors; however, those who had breast conservation were more satisfied with cosmetic outcome post-surgery as compared with mastectomy with or without reconstruction.

摘要

未标注

在许多癌症幸存者的治疗期间及之后,乳腺癌手术后的生活质量常常被忽视。提升患者生活的这一方面应是每种癌症治疗的首要目标。因此,本研究旨在突出保乳手术(BCS)、有或无重建的全乳切除术后的生活质量以及患者对乳房美容效果的满意度。

材料与方法

前瞻性收集了2015年1月1日至2021年12月31日在本机构接受乳房手术的癌症患者的数据。使用经过验证的Breast-Q问卷进行患者访谈,并使用单因素方差分析/克鲁斯卡尔 - 沃利斯检验比较三个队列之间的平均得分。

结果

总体而言,招募了210名患者,其中70名患者(33.3%)接受了保乳手术,71名患者(33.8%)仅接受了全乳切除术,69名患者(32.9%)接受了乳房重建的全乳切除术。三组之间的身体幸福感得分一致,而接受乳房重建的全乳切除术患者在性健康和心理社会健康指标上的得分高于全乳切除术患者。然而,与接受乳房重建和未接受重建的全乳切除术患者相比,保乳手术患者对其美容效果最为满意。

结论

乳房切除术后重建对幸存者的性健康和心理社会幸福感有积极影响;然而,与有或无重建的乳房切除术相比,接受保乳手术的患者对术后美容效果更满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e055/10205257/4a5393fc9f45/ms9-85-1513-g001.jpg

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