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矽肺所致肺血管狭窄患者成功同期行肺动脉和肺静脉支架置入术。病例报告及文献复习

Successful simultaneous stenting of a pulmonary artery and vein in pulmonary vascular stenosis due to silicosis. Case report and literature review.

作者信息

Westhoff M, Hardebusch T, Litterst P, Breithecker A, Haas M, Kuniss M, Neumann T, Guth S, Wiedenroth C B

机构信息

Department of Pulmonology, Klinik für Pneumologie, Schlaf und Beatmungsmedizin, Lungenklinik Hemer, Zentrum für Pneumologie und Thoraxchirurgie, Hemer, Germany.

Universität Witten/Herdecke University, Witten, Germany.

出版信息

Front Cardiovasc Med. 2023 May 9;10:1108768. doi: 10.3389/fcvm.2023.1108768. eCollection 2023.

Abstract

A 58-year-old patient was admitted to the emergency department due to severe respiratory insufficiency. Anamnesis revealed that the patient had experienced increasing stress dyspnea for a few months. Upon imaging, an acute pulmonary embolism was excluded, but peribronchial and hilar soft tissue proliferation with compression of central parts of the pulmonary circulation was found. The patient had a history of silicosis. The histology report showed tumor-free lymph node particles with prominent anthracotic pigment and dust depositions without evidence of IgG4-associated disease. The patient was administered steroid therapy and underwent simultaneous stenting of the left interlobular pulmonary artery and the upper right pulmonary vein. As a result, a significant improvement in symptoms and physical performance was achieved. The diagnosis of inflammatory or, in particular, fibrosing mediastinal processes can be challenging and important clinical symptoms must be taken into account, especially if the pulmonary vasculature is involved. In such cases, the possibility of interventional procedures should be examined in addition to drug therapy options.

摘要

一名58岁患者因严重呼吸功能不全被收治入急诊科。既往史显示患者数月来应激性呼吸困难逐渐加重。影像学检查排除了急性肺栓塞,但发现支气管周围和肺门软组织增生,压迫肺循环中心部分。该患者有矽肺病史。组织学报告显示无肿瘤的淋巴结颗粒,有明显的炭末色素和粉尘沉积,无IgG4相关疾病证据。给予该患者类固醇治疗,并同时对左肺小叶间动脉和右上肺静脉进行支架置入。结果,症状和身体状况有显著改善。炎症性,尤其是纤维化纵隔病变的诊断可能具有挑战性,必须考虑重要的临床症状,特别是如果累及肺血管时。在这种情况下,除药物治疗方案外,还应检查介入治疗的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf61/10203551/1616bf96cae2/fcvm-10-1108768-g001.jpg

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本文引用的文献

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Pulmonary Hypertension Caused by Fibrosing Mediastinitis.纤维性纵隔炎所致肺动脉高压
JACC Asia. 2022 May 17;2(3):218-234. doi: 10.1016/j.jacasi.2021.11.016. eCollection 2022 Jun.
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