Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
MacDonald Franklin OSI Research Centre, St Joseph's Health Care London, London, Ontario, Canada.
Occup Environ Med. 2023 Aug;80(8):462-468. doi: 10.1136/oemed-2022-108772. Epub 2023 May 25.
Previous research comparing veteran and civilian mental health (MH) outcomes often assumes stable rates of MH service use over time and relies on standardisation or restriction to adjust for differences in baseline characteristics. We aimed to explore the stability of MH service use in the first 5 years following release from the Canadian Armed Forces and the Royal Canadian Mounted Police, and to demonstrate the impact of using increasingly stringent matching criteria on effect estimates when comparing veterans with civilians, using incident outpatient MH encounters as an example.
We used administrative healthcare data from veterans and civilians residing in Ontario, Canada to create three hard-matched civilian cohorts: (1) age and sex; (2) age, sex and region of residence; and (3) age, sex, region of residence and median neighbourhood income quintile, while excluding civilians with a history of long-term care or rehabilitation stay or receipt of disability/income support payments. Extended Cox models were used to estimate time-dependent HRs.
Across all cohorts, time-dependent analyses suggested that veterans had a significantly higher hazard of an outpatient MH encounter within the first 3 years of follow-up than civilians, but differences were attenuated in years 4-5. More stringent matching decreased baseline differences in unmatched variables and shifted the effect estimates, while sex-stratified analyses revealed stronger effects among women compared with men.
This methods-focused study demonstrates the implications of several study design decisions that should be considered when conducting comparative veteran and civilian health research.
先前比较退伍军人和平民心理健康(MH)结果的研究通常假设 MH 服务的使用率在一段时间内是稳定的,并依赖于标准化或限制来调整基线特征的差异。我们旨在探讨退伍军人从加拿大武装部队和加拿大皇家骑警退役后 5 年内 MH 服务使用的稳定性,并以门诊 MH 就诊的发生为例,展示当比较退伍军人和平民时,使用越来越严格的匹配标准对效应估计的影响。
我们使用来自加拿大安大略省的退伍军人和平民的行政医疗保健数据,创建了三个硬匹配的平民队列:(1)年龄和性别;(2)年龄、性别和居住地区;以及(3)年龄、性别、居住地区和中值邻里收入五分位数,同时排除有长期护理或康复住院或残疾/收入支持付款史的平民。使用扩展 Cox 模型估计时间依赖性 HR。
在所有队列中,时间依赖性分析表明,退伍军人在随访的头 3 年内门诊 MH 就诊的风险明显高于平民,但在第 4-5 年时差异减弱。更严格的匹配降低了未匹配变量的基线差异,并改变了效应估计,而性别分层分析显示女性的影响比男性更强。
这项以方法为重点的研究展示了在进行退伍军人和平民健康研究时应考虑的几项研究设计决策的影响。