星状神经节阻滞导管治疗阵发性交感神经过度兴奋：平息“神经风暴”。
Stellate ganglion block catheter for paroxysmal sympathetic hyperactivity: calming the 'neuro-storm'.
机构信息
Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California, USA.
Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California, USA.
出版信息
Reg Anesth Pain Med. 2023 Oct;48(10):522-525. doi: 10.1136/rapm-2023-104399. Epub 2023 May 25.
BACKGROUND
Paroxysmal sympathetic hyperactivity (PSH) is an autonomic disorder affecting patients with severe acquired brain injury characterized by intermittent sympathetic discharges with limited therapeutic options. We hypothesized that the PSH pathophysiology could be interrupted via stellate ganglion blockade (SGB).
CASE PRESENTATION
A patient with PSH after midbrain hemorrhage followed by hydrocephalus obtained near-complete resolution of sympathetic events for 140 days after SGB.
CONCLUSION
SGB is a promising therapy for PSH, overcoming the limitations of systemic medications and may serve to recalibrate aberrant autonomic states.
背景
阵发性交感神经过度兴奋（PSH）是一种影响严重获得性脑损伤患者的自主神经障碍，其特征为间歇性交感神经放电，治疗选择有限。我们假设通过星状神经节阻滞（SGB）可以阻断 PSH 的病理生理学。
病例介绍
一位中脑出血后继发脑积水的患者，在 SGB 后 140 天几乎完全缓解了交感事件。
结论
SGB 是 PSH 的一种有前途的治疗方法，克服了全身药物治疗的局限性，并可能有助于重新校准异常的自主状态。
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