Okuda Y, Kitajima T
First Department of Anesthesiology, Dokkyo University School of Medicine Tochigi.
Masui. 1996 Dec;45(12):1465-8.
The purpose of this study was to investigate the influence of the stellate ganglion block (SGB), stellate ganglion electrical stimulation (SGES) and stellate ganglionectomy on bilateral arterial blood flows (BAF). Sixteen mongrel dogs were divided into two groups; a SGB group (n = 8) and a SGES group (n = 8). Anesthesia was induced with pentobarbital 25 mg.kg-1 and the animals were mechanically ventilated to maintain proper PaO2 (90-100 mmHg) and PaCO2 (35-40 mmHg). After a thoracotomy, the SGB with 0.5% mepivacaine 1.0 ml was performed in the SGB group. SGES was performed at a strength of 12 volts, and at a frequency of 50 Hz, applied for 15 minutes and then 15 minutes after the SGES, stellate ganglionectomy was performed in SGES group. In the SGB group, BAF in the blocked side increased significantly but BAF in the contralateral side decreased significantly after SGB. In the SGES group, bilateral BAF decreased significantly (Lt > Rt) and after the stellate ganglionectomy, bilateral BAF increased more than after SGES. These results suggest that the SGB may not be effective on the contralateral side under normal conditions, but under the conditions of sympathetic stimulation, the SGB may be effective on the contralateral side.
本研究的目的是探讨星状神经节阻滞(SGB)、星状神经节电刺激(SGES)和星状神经节切除术对双侧动脉血流(BAF)的影响。将16只杂种犬分为两组:SGB组(n = 8)和SGES组(n = 8)。用25mg·kg-1戊巴比妥诱导麻醉,动物进行机械通气以维持适当的动脉血氧分压(PaO2,90 - 100mmHg)和动脉血二氧化碳分压(PaCO2,35 - 40mmHg)。开胸后,SGB组用0.5%甲哌卡因1.0ml进行星状神经节阻滞。SGES组以12伏强度、50赫兹频率进行电刺激,持续15分钟,然后在电刺激后15分钟进行星状神经节切除术。在SGB组,星状神经节阻滞后阻滞侧的BAF显著增加,但对侧的BAF显著降低。在SGES组,双侧BAF显著降低(左侧>右侧),星状神经节切除术后,双侧BAF比电刺激后增加更多。这些结果表明,在正常情况下SGB可能对侧无效,但在交感神经刺激的情况下,SGB可能对侧有效。