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“UFO 手术”治疗累及左心房和心室心肌的巨大主动脉瓣环和二尖瓣环钙化:一种潜在的根治方法。

"UFO procedure" for massive aortic and mitral annular calcification involving left atrial and ventricular myocardium: a potential radical solution.

机构信息

Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité (DHZC), Augustenburger Platz 1, 13353, Berlin, Germany.

DZHK (German Center for Cardiovascular Research), partner site Berlin, Berlin, Germany.

出版信息

J Cardiothorac Surg. 2023 May 25;18(1):185. doi: 10.1186/s13019-023-02267-5.

Abstract

BACKGROUND

The "UFO procedure" was initially developed as a surgical option to enlarge the aortic annulus in patients requiring valve replacement. This technique can be employed to treat extensive endocarditis located in the intervalvular fibrous body (IVFB). One of the indications for a "UFO procedure" is massive aortic and mitral valve calcification. It is a challenging surgical procedure with a high risk of intraoperative complications. We present a 76-year-old male patient with massive aortic and mitral valve calcification involving the left atrium, the left ventricle and the left ventricular outflow tract. Both valves exhibited severe stenosis and moderate to severe regurgitation. The left ventricle was hypertrophic and the left ventricular ejection fraction was > 55%. The patient was prediagnosed with persistent atrial fibrillation. The risk of death following heart surgery (EuroSCORE II) was calculated as 9.21%. We successfully performed a so-called "UFO procedure" including replacement of both valves without annular decalcification to avoid atrioventricular dehiscence. We enlarged the IVFB and replaced the non-coronary sinus of Valsalva with doubled bovine pericardium. The left ventricular outflow tract was decalcified. The patient was transferred to a local hospital on the 13th postoperative day.

CONCLUSION

Successful surgical treatment to this extent was demonstrated for the first time. Due to the high perioperative mortality, the surgical treatment of patients with this constellation would be refused in most cases. In our patient, the preoperative imaging showed extreme calcification of both valves and the surrounding myocardium. Excellent preoperative planning and a highly experienced surgical team is necessary.

摘要

背景

“UFO 手术”最初是作为一种手术选择而开发的,用于扩大需要瓣膜置换的患者的主动脉瓣环。该技术可用于治疗位于瓣下纤维体(IVFB)间隔的广泛心内膜炎。“UFO 手术”的适应证之一是主动脉瓣和二尖瓣广泛钙化。这是一项具有挑战性的手术,术中并发症风险高。我们报告了一例 76 岁男性患者,其主动脉瓣和二尖瓣广泛钙化累及左心房、左心室和左心室流出道。两个瓣膜均有严重狭窄和中度至重度反流。左心室肥厚,左心室射血分数>55%。患者被诊断为持续性心房颤动。心脏手术后死亡风险(EuroSCORE II)计算为 9.21%。我们成功地进行了所谓的“UFO 手术”,包括在不进行环形去钙化的情况下更换两个瓣膜,以避免房室分离。我们扩大了 IVFB,并使用双倍牛心包替换了非冠状动脉窦。左心室流出道去钙化。患者于术后第 13 天转至当地医院。

结论

首次成功进行了如此程度的手术治疗。由于围手术期死亡率高,大多数情况下会拒绝对此类患者进行手术治疗。在我们的患者中,术前影像学显示两个瓣膜和周围心肌严重钙化。需要进行出色的术前规划和具有丰富经验的手术团队。

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