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主动脉瓣和二尖瓣置换术联合瓣间纤维体重建术。

Aortic and mitral valve replacement with reconstruction of the intervalvular fibrous body.

作者信息

David T E, Kuo J, Armstrong S

机构信息

Division of Cardiovascular Surgery, Toronto Hospital, Ontario, Canada.

出版信息

J Thorac Cardiovasc Surg. 1997 Nov;114(5):766-71; discussion 771-2. doi: 10.1016/S0022-5223(97)70080-1.

Abstract

OBJECTIVE

The intervalvular fibrous body between the aortic and mitral valves can be damaged by infective endocarditis, degenerative calcification, or multiple previous heart valve operations, making double valve replacement difficult. We have managed this problem by approaching the aortic and mitral valves through the aortic root and the dome of the left atrium. After excising the aortic valve, the diseased fibrous body, and the mitral valve, we suture a properly tailored patch of Dacron fabric or bovine pericardium to the lateral and medial fibrous trigones and to the aortic root, reestablishing the aortic and mitral anuli. A prosthetic mitral valve is implanted and a separate patch is used to close the left atriotomy before implantation of a prosthetic aortic valve. This study was undertaken to determine the efficacy of this operation.

METHODS

Forty-three patients underwent reconstruction of the intervalvular fibrous body during aortic and mitral valve replacement because of infective endocarditis with abscess in 14 patients, extensive calcification in 9, lack of fibrous tissue because of multiple previous operations in 10, and to enlarge the aortic and mitral anuli in 10. The group comprised 18 men and 25 women with a mean age of 58 +/- 12 years. Thirty-two patients had had one or more previous heart valve replacements. All patients were in New York Heart Association functional classes III and IV, and 9 patients were in shock before the operation.

RESULTS

Seven operative deaths occurred (16%). Early prosthetic valve endocarditis developed in two patients and necessitated reoperation. Follow-up extended from 4 to 108 months, with a mean of 38 months. No patient was lost to follow-up. Six late deaths occurred. The actuarial survival at 6 years was 56% +/- 6%. A Doppler echocardiographic study revealed normal prosthetic valve function and anatomically intact anuli in all 30 long-term survivors.

CONCLUSIONS

Reconstruction of the intervalvular fibrous body during aortic and mitral valve replacement is a satisfactory operative approach in patients with complex valve annular pathology.

摘要

目的

主动脉瓣与二尖瓣之间的瓣间纤维体可因感染性心内膜炎、退行性钙化或多次既往心脏瓣膜手术而受损,导致双瓣膜置换术难度增大。我们通过经主动脉根部和左心房顶部处理主动脉瓣和二尖瓣来解决这一问题。切除主动脉瓣、病变的纤维体和二尖瓣后,我们将一块裁剪合适的涤纶织物或牛心包补片缝合至外侧和内侧纤维三角以及主动脉根部,重建主动脉瓣环和二尖瓣环。植入人工二尖瓣,在植入人工主动脉瓣之前,使用单独的补片关闭左心房切口。本研究旨在确定该手术的疗效。

方法

43例患者在主动脉瓣和二尖瓣置换术中进行了瓣间纤维体重建,其中14例因感染性心内膜炎合并脓肿,9例因广泛钙化,10例因多次既往手术导致纤维组织缺失,10例因主动脉瓣环和二尖瓣环扩大。该组包括18名男性和25名女性,平均年龄为58±12岁。32例患者曾接受过一次或多次心脏瓣膜置换术。所有患者均处于纽约心脏协会心功能Ⅲ级和Ⅳ级,9例患者术前处于休克状态。

结果

发生7例手术死亡(16%)。2例患者发生早期人工瓣膜心内膜炎,需要再次手术。随访时间为4至108个月,平均38个月。无患者失访。发生6例晚期死亡。6年时的精算生存率为56%±6%。多普勒超声心动图研究显示,所有30例长期存活者的人工瓣膜功能正常,瓣环解剖结构完整。

结论

对于存在复杂瓣环病变的患者,在主动脉瓣和二尖瓣置换术中重建瓣间纤维体是一种令人满意的手术方法。

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