De Oliveira Nilto C, David Tirone E, Armstrong Susan, Ivanov Joan
Division of Cardiovascular Surgery of Toronto General Hospital and University of Toronto, Toronto, Ontario, Canada.
J Thorac Cardiovasc Surg. 2005 Feb;129(2):286-90. doi: 10.1016/j.jtcvs.2004.09.032.
This study was undertaken to evaluate the late outcomes of reconstruction of the intervalvular fibrous body during aortic and mitral valve replacement.
Seventy-six consecutive patients underwent reconstruction of the intervalvular fibrous body with replacement of the mitral and aortic valves. There were 35 men and 41 women whose mean age was 58 +/- 12 years. Additional procedures were circumferential reconstruction of the mitral annulus in 27 patients, tricuspid valve repair in 21, coronary artery bypass in 15, and aortic root replacement in 4. Indications for the operation were active infective endocarditis with abscess in 15 patients, extensive calcification of the mitral annulus and interventricular fibrous body in 24, lack of fibrous tissue to secure a prosthetic valve in 17, and treatment or prevention of patient-prosthesis mismatch in 20. Fifty-five patients had undergone one or more previous valve operations, and 52 (68%) were in functional class IV. The mean follow-up was 47 +/- 47 months, and it was complete.
There were 8 (10%) operative and 18 (24%) late deaths. The 10-year survival was 50% +/- 9%. There were 15 reoperations in 12 patients: 7 for prosthetic valve endocarditis (5 early, 2 late), 7 for patch or valve dehiscence (3 early, 4 late), and 1 for structural valve deterioration. All but 2 reoperations were re-reconstruction of the intervalvular fibrous body and double valve replacement. The 10-year freedom from reoperation was 73% +/- 7%.
Reconstruction of the intervalvular fibrous body during double valve replacement is a technically challenging operation, but it is useful in patients with complex valve pathology for whom no alternative procedure is available.
本研究旨在评估主动脉瓣和二尖瓣置换术中瓣间纤维体重建的远期疗效。
连续76例患者接受了瓣间纤维体重建及二尖瓣和主动脉瓣置换术。其中男性35例,女性41例,平均年龄58±12岁。另外,27例患者进行了二尖瓣环周向重建,21例进行了三尖瓣修复,15例进行了冠状动脉搭桥,4例进行了主动脉根部置换。手术适应证包括:15例活动性感染性心内膜炎伴脓肿,24例二尖瓣环和室间纤维体广泛钙化,17例缺乏固定人工瓣膜的纤维组织,20例治疗或预防人工瓣膜与患者不匹配。55例患者曾接受过一次或多次瓣膜手术,52例(68%)心功能为IV级。平均随访时间为47±47个月,随访完整。
手术死亡8例(10%),晚期死亡18例(24%)。10年生存率为50%±9%。12例患者进行了15次再次手术:7例因人工瓣膜心内膜炎(5例早期,2例晚期),7例因补片或瓣膜裂开(3例早期,4例晚期),1例因人工瓣膜结构损坏。除2例再次手术外,其余均为瓣间纤维体重建及双瓣膜置换。10年免于再次手术率为73%±7%。
双瓣膜置换术中瓣间纤维体重建是一项技术要求较高的手术,但对于没有其他替代手术方案的复杂瓣膜病变患者是有用的。