Ichimiya Y, Kobayashi K, Arai H, Ikeda K, Kosaka K
J Neurol. 1986 Jun;233(3):164-7. doi: 10.1007/BF00314425.
Seventeen patients with clinically diagnosed Alzheimer's disease and 13 healthy age-matched controls were studied by means of computed tomography (CT). To assess cerebral atrophy, regional volumetric measurements and parenchymal density measurements were performed. The results indicate that: (1) Alzheimer patients show diffuse cerebral atrophy in the early stage; (2) the evaluation of lobar atrophy by means of CT is useful for the clinical diagnosis of Alzheimer's disease; (3) the evaluation of parenchymal density by means of CT is not as sensitive as the evaluation of lobar atrophy.
对17例临床诊断为阿尔茨海默病的患者和13例年龄匹配的健康对照者进行了计算机断层扫描（CT）研究。为评估脑萎缩，进行了区域体积测量和实质密度测量。结果表明：（1）阿尔茨海默病患者在早期表现为弥漫性脑萎缩；（2）通过CT评估脑叶萎缩对阿尔茨海默病的临床诊断有用；（3）通过CT评估实质密度不如评估脑叶萎缩敏感。
