一项通过区域容积和实质密度测量对阿尔茨海默病进行的计算机断层扫描研究。

A computed tomography study of Alzheimer's disease by regional volumetric and parenchymal density measurements.

作者信息

Ichimiya Y, Kobayashi K, Arai H, Ikeda K, Kosaka K

出版信息

J Neurol. 1986 Jun;233(3):164-7. doi: 10.1007/BF00314425.

Abstract

Seventeen patients with clinically diagnosed Alzheimer's disease and 13 healthy age-matched controls were studied by means of computed tomography (CT). To assess cerebral atrophy, regional volumetric measurements and parenchymal density measurements were performed. The results indicate that: (1) Alzheimer patients show diffuse cerebral atrophy in the early stage; (2) the evaluation of lobar atrophy by means of CT is useful for the clinical diagnosis of Alzheimer's disease; (3) the evaluation of parenchymal density by means of CT is not as sensitive as the evaluation of lobar atrophy.

摘要

对17例临床诊断为阿尔茨海默病的患者和13例年龄匹配的健康对照者进行了计算机断层扫描（CT）研究。为评估脑萎缩，进行了区域体积测量和实质密度测量。结果表明：（1）阿尔茨海默病患者在早期表现为弥漫性脑萎缩；（2）通过CT评估脑叶萎缩对阿尔茨海默病的临床诊断有用；（3）通过CT评估实质密度不如评估脑叶萎缩敏感。