A new iridoid glucoside from the roots of .

A new iridoid glucoside, moridoside (), and nine known compounds, asperulosidic acid (), 6---acetylscandoside (), geniposidic acid (), 2-hydroxymethylanthraquinone (), 2-hydroxymethyl-3-hydroxyanthraquinone (), damnacanthol (), lucidine-ω-methyl ether (), 2-hydroxy-1-methoxyanthraquinone (), and 3,8-dihydroxy-1,2-dimethoxyanthraquinone () were isolated from the methanol extract of How. roots. Their structural identification was carried out based on the spectroscopic evidence. All compounds were evaluated for their nitric oxide (NO) production inhibitory activities in LPS-stimulated RAW264.7 macrophages. Compounds significantly inhibited the production of NO with IC values of 28.4, 33.6, and 30.5 μM, respectively.