β-榄香烯通过抑制结直肠癌的增殖、转移和抗凋亡发挥抗癌作用。 - Suppr

Anticancer effects of β-elemene via inhibition of proliferation, metastasis, and antiapoptosis in colorectal cancer.

作者信息

Tian Jun, Wang Chenyu, Zhu Yimiao, Xu Xiaozhong, Yao Xuequan, Wu Xiaoyu

机构信息

Department of General Surgery, Zhangjiagang Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou, China.

First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, China.

出版信息

Minerva Gastroenterol (Torino). 2023 May 26. doi: 10.23736/S2724-5985.23.03440-X.

DOI:10.23736/S2724-5985.23.03440-X

PMID:37232145

Abstract

摘要

相似文献

Anticancer effects of β-elemene via inhibition of proliferation, metastasis, and antiapoptosis in colorectal cancer.β-榄香烯通过抑制结直肠癌的增殖、转移和抗凋亡发挥抗癌作用。

Minerva Gastroenterol (Torino). 2023 May 26. doi: 10.23736/S2724-5985.23.03440-X.

β-Elemene inhibits the metastasis of multidrug-resistant gastric cancer cells through miR-1323/Cbl-b/EGFR pathway.β-榄香烯通过 miR-1323/Cbl-b/EGFR 通路抑制多药耐药胃癌细胞的转移。

Phytomedicine. 2020 Apr;69:153184. doi: 10.1016/j.phymed.2020.153184. Epub 2020 Feb 10.

β-Elemene Reverses the Resistance of p53-Deficient Colorectal Cancer Cells to 5-Fluorouracil by Inducing Pro-death Autophagy and Cyclin D3-Dependent Cycle Arrest.β-榄香烯通过诱导促死亡自噬和细胞周期蛋白D3依赖性细胞周期阻滞逆转p53缺陷型结肠癌细胞对5-氟尿嘧啶的耐药性。

Front Bioeng Biotechnol. 2020 May 8;8:378. doi: 10.3389/fbioe.2020.00378. eCollection 2020.

β-Elemene induces apoptosis and autophagy in colorectal cancer cells through regulating the ROS/AMPK/mTOR pathway.β-榄香烯通过调控 ROS/AMPK/mTOR 通路诱导结直肠癌细胞凋亡和自噬。

Chin J Nat Med. 2022 Jan;20(1):9-21. doi: 10.1016/S1875-5364(21)60118-8.

β-elemene suppresses tumor metabolism and stem cell-like properties of non-small cell lung cancer cells by regulating PI3K/AKT/mTOR signaling.β-榄香烯通过调节PI3K/AKT/mTOR信号通路抑制非小细胞肺癌细胞的肿瘤代谢和干细胞样特性。

Am J Cancer Res. 2022 Apr 15;12(4):1535-1555. eCollection 2022.

Molecular targets of β-elemene, a herbal extract used in traditional Chinese medicine, and its potential role in cancer therapy: A review.β-榄香烯，一种中药提取物的分子靶点及其在癌症治疗中的潜在作用：综述。

Biomed Pharmacother. 2019 Jun;114:108812. doi: 10.1016/j.biopha.2019.108812. Epub 2019 Apr 6.

Sensitization of lung cancer cells to cisplatin by β-elemene is mediated through blockade of cell cycle progression: antitumor efficacies of β-elemene and its synthetic analogs.β-榄香烯通过阻断细胞周期进程增敏肺癌细胞对顺铂的敏感性：β-榄香烯及其合成类似物的抗肿瘤疗效。

Med Oncol. 2013 Mar;30(1):488. doi: 10.1007/s12032-013-0488-9. Epub 2013 Feb 9.

Beta-elemene inhibits breast cancer metastasis through blocking pyruvate kinase M2 dimerization and nuclear translocation.β-榄香烯通过阻断丙酮酸激酶 M2 二聚化和核转位抑制乳腺癌转移。

J Cell Mol Med. 2019 Oct;23(10):6846-6858. doi: 10.1111/jcmm.14568. Epub 2019 Jul 25.

Beta-elemene inhibits differentiated thyroid carcinoma metastasis by reducing cellular proliferation, metabolism and invasion ability.β-榄香烯通过降低细胞增殖、代谢和侵袭能力来抑制分化型甲状腺癌转移。

Ann Transl Med. 2020 Oct;8(19):1232. doi: 10.21037/atm-20-4460.

Anticancer effects of β-elemene in gastric cancer cells and its potential underlying proteins: a proteomic study.β-榄香烯对胃癌细胞的抗癌作用及其潜在相关蛋白：一项蛋白质组学研究

Oncol Rep. 2014 Dec;32(6):2635-47. doi: 10.3892/or.2014.3490. Epub 2014 Sep 17.

引用本文的文献

The Novel Elemene Derivative, OMe-Ph-Elemene, Attenuates Oxidative Phosphorylation and Facilitates Apoptosis by Inducing Intracellular Reactive Oxygen Species.新型榄香烯衍生物OMe-Ph-榄香烯通过诱导细胞内活性氧来减弱氧化磷酸化并促进细胞凋亡。

Antioxidants (Basel). 2024 Dec 9;13(12):1499. doi: 10.3390/antiox13121499.

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Anticancer effects of β-elemene via inhibition of proliferation, metastasis, and antiapoptosis in colorectal cancer.

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