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儿童穿孔性阑尾炎治疗中可避免的过度治疗

The avoidable excesses in the management of perforated appendicitis in children.

作者信息

Karp M P, Caldarola V A, Cooney D R, Allen J E, Jewett T C

出版信息

J Pediatr Surg. 1986 Jun;21(6):506-10. doi: 10.1016/s0022-3468(86)80221-4.

Abstract

During a five-year period from 1979 to 1985, 100 consecutive children with perforated appendicitis were managed at our institution. These patients were divided into two groups, which were determined by length of illness and physical findings. Group A consisted of 88 children with signs and symptoms of peritonitis from appendiceal perforation. They were treated with fluid resuscitation, antipyretics, and triple antibiotics (ampicillin, gentamicin, clindamycin), and appendectomy within a few hours of hospitalization. Saline lavage was used. Group B was composed of 12 patients with a periappendiceal mass without generalized peritonitis who had symptoms of 6 to 12 days duration. They were treated nonoperatively with triple antibiotics and underwent interval appendectomy 4 to 6 weeks later. The complication rate for Group A was 6.8%. This included three wound infections (3.4%), one intra-abdominal abscess (1.1%), one patient with pneumonia and ileus (1.1%), and a small bowel obstruction (1.1%). These results are equivalent to the lowest complication rate reported in the literature, in which the treatment included transperitoneal drainage, antibiotic lavage, and parenteral antibiotics. Group B patients had a 16.7% complication rate, which included one small bowel obstruction and one recurrent intra-abdominal abscess. Our method of management resulted in the lowest complication rate reported to date in children with perforated appendicitis. Transperitoneal drainage, delayed wound closure, and antibiotic lavage were not used. Subcuticular incisional closure resulted in minimal wound care and excellent cosmetic results. The experience demonstrates that with proper timing of surgery and appropriate use of contemporary antibiotics, the morbidity of perforated appendicitis can be limited and excesses of treatment can be avoided.

摘要

在1979年至1985年的五年期间,我院连续收治了100例穿孔性阑尾炎患儿。这些患者根据病程长短和体格检查结果分为两组。A组由88例阑尾穿孔并发腹膜炎体征和症状的患儿组成。他们接受了液体复苏、退烧药和三联抗生素(氨苄西林、庆大霉素、克林霉素)治疗,并在住院后数小时内接受了阑尾切除术。采用了生理盐水灌洗。B组由12例阑尾周围脓肿且无弥漫性腹膜炎的患者组成,其症状持续6至12天。他们接受了三联抗生素非手术治疗,并在4至6周后接受了间隔期阑尾切除术。A组的并发症发生率为6.8%。其中包括3例伤口感染(3.4%)、1例腹腔内脓肿(1.1%)、1例肺炎合并肠梗阻患者(1.1%)和1例小肠梗阻(1.1%)。这些结果与文献报道的最低并发症发生率相当,文献中的治疗方法包括经腹引流、抗生素灌洗和胃肠外抗生素治疗。B组患者的并发症发生率为16.7%,包括1例小肠梗阻和1例复发性腹腔内脓肿。我们的治疗方法导致了迄今为止报道的穿孔性阑尾炎患儿最低的并发症发生率。未采用经腹引流、延迟伤口缝合和抗生素灌洗。皮下缝合切口导致伤口护理最少且美容效果极佳。该经验表明,通过适当的手术时机和合理使用现代抗生素,可以限制穿孔性阑尾炎的发病率并避免过度治疗。

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