红细胞分布宽度是老年感染患者多器官功能障碍综合征的危险因素：一项病例对照研究。
Red blood cell distribution width is a risk factor for multiple organ dysfunction syndrome in elderly patients with infection: a case control study.
机构信息
Department of Geriatrics, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.
Special Service Department, No. 989 Hospital of the PLA Joint Logistic Support Force, Pingdingshan, 467000, China.
出版信息
Aging Clin Exp Res. 2023 Jul;35(7):1577-1580. doi: 10.1007/s40520-023-02431-w. Epub 2023 May 26.
BACKGROUND
Infection is the leading cause of multiple organ dysfunction syndrome (MODS) in the elderly. Red blood cell distribution width (RDW) was considered to be associated with many diseases. We aimed to explore whether RDW was associated with MODS in elderly infected patients.
METHODS
We retrospectively collected data from elderly patients (≥ 65 years old) with infection. In this study, we conducted a 1:3 case-control match based on age and gender and utilized binary Logistic regression to investigate the impact of variables such as RDW on MODS.
RESULTS
A total of 576 eligible patients were included in this study. RDW in the case group was significantly higher than that in control group (p < 0.001). Multivariate analysis found that RDW was an independent risk factor for MODS in elderly infected patients (OR = 1.397, 95% CI: 1.166-1.674, p < 0.001).
CONCLUSIONS
RDW was an independent risk factor for MODS in elderly patients with infection.
背景
感染是老年人多器官功能障碍综合征（MODS）的主要原因。红细胞分布宽度（RDW）被认为与许多疾病有关。我们旨在探讨 RDW 是否与感染的老年患者的 MODS 相关。
方法
我们回顾性地收集了感染的老年患者（≥65 岁）的数据。在这项研究中，我们根据年龄和性别进行了 1:3 的病例对照匹配，并利用二元 Logistic 回归分析了 RDW 等变量对 MODS 的影响。
结果
共有 576 名符合条件的患者纳入本研究。病例组的 RDW 明显高于对照组（p<0.001）。多变量分析发现，RDW 是感染老年患者发生 MODS 的独立危险因素（OR=1.397，95%CI：1.166-1.674，p<0.001）。
结论
RDW 是感染老年患者发生 MODS 的独立危险因素。
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