大肠杆菌将甲硫氨酸亚砜还原为甲硫氨酸。
Reduction of methionine sulfoxide to methionine by Escherichia coli.
作者信息
Ejiri S I, Weissbach H, Brot N
出版信息
J Bacteriol. 1979 Jul;139(1):161-4. doi: 10.1128/jb.139.1.161-164.1979.
Abstract
L-Methionine-dl-sulfoxide can support the growth of an Escherichia coli methionine auxotroph, suggesting the presence of an enzyme(s) capable of reducing the sulfoxide to methionine. This was verified by showing that a cell-free extract of E. coli catalyzes the conversion of methionine sulfoxide to methionine. This reaction required reduced nicotinamide adenine dinucleotide phosphate and a generating system for this compound. The specific activity of the enzyme increased during logarithmic growth and was maximal when the culture attained a density of about 10(9) cells per ml.
摘要
L-蛋氨酸-dl-亚砜能够支持大肠杆菌蛋氨酸营养缺陷型菌株的生长，这表明存在一种能够将亚砜还原为蛋氨酸的酶。通过证明大肠杆菌的无细胞提取物催化蛋氨酸亚砜向蛋氨酸的转化，这一点得到了验证。该反应需要还原型烟酰胺腺嘌呤二核苷酸磷酸以及该化合物的生成系统。该酶的比活性在对数生长期增加，当培养物密度达到约每毫升10(9)个细胞时达到最大值。
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