Krishnamoorthi Sivanantham, Goel Shriya, Kaur Jasleen, Bisht Kamlesh, Biswal Manisha
Department of Microbiology, All India Institute of Medical Sciences, Bathinda 151001, India.
Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.
Trop Med Infect Dis. 2023 May 16;8(5):280. doi: 10.3390/tropicalmed8050280.
Rickettsial diseases (RD) are widely reported all over the world. Scrub typhus (ST) is a major tropical infection which is well documented all over India. Therefore, the index of suspicion of scrub typhus is high among physicians with regard to patients presenting with acute febrile illness (AFI) and acute undifferentiated febrile illness (AUFI) in India. Rickettsial diseases other than ST (non-ST RDs), which include spotted fever group (SFG) rickettsioses and typhus group (TG) rickettsioses are not uncommon in India, but the index of suspicion is not as high as ST unless there is a history of the presence of fever with rashes and/or recent arthropod bites. This review aims to look into the Indian scenario on the epidemiology of non-ST RDs, especially the SFG and TG rickettsioses based on various investigations, spectrum of clinical presentation, challenges and gaps in knowledge to suspect and diagnose these infections.
立克次体病（RD）在世界各地均有广泛报道。恙虫病（ST）是一种主要的热带感染病，在印度各地都有详细记录。因此，在印度，对于患有急性发热性疾病（AFI）和急性未分化发热性疾病（AUFI）的患者，医生对恙虫病的怀疑指数很高。除恙虫病外的立克次体病（非ST立克次体病），包括斑点热群（SFG）立克次体病和斑疹伤寒群（TG）立克次体病，在印度并不罕见，但除非有发热伴皮疹和/或近期节肢动物叮咬史，否则怀疑指数不如恙虫病高。本综述旨在基于各种调查、临床表现谱、怀疑和诊断这些感染的知识挑战与差距，探讨印度非ST立克次体病的流行病学情况，尤其是SFG和TG立克次体病。
