College of Health, The University of Montana, Missoula, MT 59812, USA; Universidad del Valle de México, Mexico City 14370, Mexico.
Sacramento Metropolitan Air Quality Management District, Sacramento, CA 95814, USA; West Virginia University, Morgantown, WV 26506, USA.
Cell. 2023 May 25;186(11):2285-2287. doi: 10.1016/j.cell.2023.04.033.
Exposures to fine particulate matter (PM) concentrations above the WHO guidelines affect 99% of the world population. In a recent issue of Nature, Hill et al. dissect the tumor promotion paradigm orchestrated by PM inhalation exposures in lung carcinogenesis, supporting the hypothesis that PM can increase your risk of lung carcinoma without ever smoking.
细颗粒物 (PM) 浓度超过世界卫生组织指南的暴露影响了全球 99%的人口。在最近一期的《自然》杂志上,Hill 等人剖析了 PM 吸入暴露在肺癌发生中所调控的肿瘤促进模式,支持了这样一种假设,即 PM 即使不吸烟也会增加患肺癌的风险。