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Modulating GPCR and 14-3-3 protein interactions: Prospects for CNS drug discovery.
Drug Discov Today. 2023 Aug;28(8):103641. doi: 10.1016/j.drudis.2023.103641. Epub 2023 May 24.
2
14-3-3 signal adaptor and scaffold proteins mediate GPCR trafficking.
Sci Rep. 2019 Aug 1;9(1):11156. doi: 10.1038/s41598-019-47478-w.
3
β-arrestins and G protein-coupled receptor trafficking.
Handb Exp Pharmacol. 2014;219:173-86. doi: 10.1007/978-3-642-41199-1_9.
4
Signal transduction at GPCRs: Allosteric activation of the ERK MAPK by β-arrestin.
Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2303794120. doi: 10.1073/pnas.2303794120. Epub 2023 Oct 16.
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Screening β-arrestin recruitment for the identification of natural ligands for orphan G-protein-coupled receptors.
J Biomol Screen. 2013 Jun;18(5):599-609. doi: 10.1177/1087057113475480. Epub 2013 Feb 8.
6
Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression.
Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):E5160-8. doi: 10.1073/pnas.1508836112. Epub 2015 Aug 31.
7
Subcellular Organization of GPCR Signaling.
Trends Pharmacol Sci. 2018 Feb;39(2):200-208. doi: 10.1016/j.tips.2017.11.009. Epub 2018 Jan 28.
8
β-arrestin signalling and bias in hormone-responsive GPCRs.
Mol Cell Endocrinol. 2017 Jul 5;449:28-41. doi: 10.1016/j.mce.2017.01.052. Epub 2017 Feb 4.
9
Terminating G-Protein Coupling: Structural Snapshots of GPCR-β-Arrestin Complexes.
Cell. 2020 Mar 19;180(6):1041-1043. doi: 10.1016/j.cell.2020.02.047. Epub 2020 Mar 12.
10
Structural mechanism of GPCR-arrestin interaction: recent breakthroughs.
Arch Pharm Res. 2016 Mar;39(3):293-301. doi: 10.1007/s12272-016-0712-1. Epub 2016 Jan 29.

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1
Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors.
Science. 2023 Feb 17;379(6633):700-706. doi: 10.1126/science.adf0435. Epub 2023 Feb 16.
2
Taking the tripping out of psychedelic medicine.
Nature. 2022 Sep;609(7929):S80-S82. doi: 10.1038/d41586-022-02869-4.
3
The psychedelic escape from depression.
Nature. 2022 Sep;609(7929):S87-S89. doi: 10.1038/d41586-022-02872-9.
4
Ligands can differentially and temporally modulate GPCR interaction with 14-3-3 isoforms.
Curr Res Pharmacol Drug Discov. 2022 Aug 7;3:100123. doi: 10.1016/j.crphar.2022.100123. eCollection 2022.
5
The 14-3-3 Protein Family and Schizophrenia.
Front Mol Neurosci. 2022 Mar 14;15:857495. doi: 10.3389/fnmol.2022.857495. eCollection 2022.
6
Opioid overdose and tolerance: is the recruitment of β-arrestin to the µ-receptor involved?
Neuropsychopharmacology. 2021 Dec;46(13):2226-2227. doi: 10.1038/s41386-021-01121-3. Epub 2021 Aug 16.
8
Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo.
Neuron. 2021 Aug 18;109(16):2535-2544.e4. doi: 10.1016/j.neuron.2021.06.008. Epub 2021 Jul 5.
10
Identification of 14-3-3 epsilon as a regulator of the neural apoptotic pathway for chronic-stress-induced depression.
iScience. 2021 Jan 8;24(2):102043. doi: 10.1016/j.isci.2021.102043. eCollection 2021 Feb 19.

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