早产儿6个月大时颅骨形状和发育商数的变化。

Changes in Cranial Shape and Developmental Quotient at 6 Months of Age in Preterm Infants.

作者信息

Nakanomori Aya, Miyabayashi Hiroshi, Tanaka Yukari, Maedomari Taishin, Mukai Chihiro, Saito Katsuya, Okahashi Aya, Nagano Nobuhiko, Morioka Ichiro

机构信息

Department of Pediatrics and Child Health, Nihon University School of Medicine, Tokyo 173-8610, Japan.

Department of Pediatrics, Kasukabe Medical Center, Saitama 344-8588, Japan.

出版信息

Children (Basel). 2023 May 11;10(5):855. doi: 10.3390/children10050855.

DOI:10.3390/children10050855

PMID:37238403

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10217116/

Abstract

The purpose of this study was to investigate changes in cranial shape among preterm neonates aged 1-6 months and the relationship between developmental quotient (DQ) and cranial shape at 6 months of age. Preterm infants who were hospitalized in our hospital were prospectively followed for 6 months. The cephalic index (CI) and cranial vault asymmetry index (CVAI) were evaluated at 1 (T1), 3 (T2), and 6 months (T3) of age and compared with those of the full-term infants. The relationship between CI or CVAI and DQ at T3 was analyzed using the Enjoji Scale of Infant Analytical Development. A total of 26 participants born at 34.7 ± 1.9 weeks of gestation were included. The CI increased with age (T1: 77.2%, T2: 82.9%, T3: 85.4%, < 0.01). The prevalence of dolichocephaly at T3 did not significantly differ from that in full-term infants (15.4% vs. 4.5%, = 0.08). CVAI did not significantly differ between preterm and full-term infants. The DQ showed no significant correlation with either the CI or CVAI (correlation coefficients: 0.23 for CI, -0.01; CVAI). Dolichocephaly improved over time in preterm infants and no relationship between cranial shape and development was observed in preterm infants at 6 months of age.

摘要

本研究的目的是调查1至6个月大的早产儿颅骨形状的变化以及6个月大时发育商（DQ）与颅骨形状之间的关系。对我院住院的早产儿进行了为期6个月的前瞻性随访。在1个月（T1）、3个月（T2）和6个月（T3）时评估头指数（CI）和颅穹不对称指数（CVAI），并与足月儿进行比较。使用婴儿分析发育恩乔吉量表分析T3时CI或CVAI与DQ之间的关系。共纳入26名妊娠34.7±1.9周出生的参与者。CI随年龄增加（T1：77.2%，T2：82.9%，T3：85.4%，<0.01）。T3时长头畸形的患病率与足月儿无显著差异（15.4%对4.5%，=0.08）。早产儿和足月儿的CVAI无显著差异。DQ与CI或CVAI均无显著相关性（相关系数：CI为0.23，CVAI为-0.01）。早产儿的长头畸形随时间改善，6个月大的早产儿未观察到颅骨形状与发育之间的关系。