Ciarambino Tiziana, Crispino Pietro, Minervini Giovanni, Giordano Mauro
Internal Medicine Department, Hospital of Marcianise, ASL Caserta, 81024 Caserta, Italy.
Internal Medicine Department, Hospital of Latina, ASL Latina, 04100 Latina, Italy.
Biomedicines. 2023 Apr 26;11(5):1280. doi: 10.3390/biomedicines11051280.
Cerebral sinus venous thrombosis (CSVT) is a relatively rare acute disorder of cerebral circulation, but it can potentially be associated with serious sequelae and a poor prognosis. The neurological manifestations associated with it are often not adequately taken into consideration given the extreme variability and nuances of its clinical presentation and given the need for radiological methods suitable for this type of diagnosis. CSVT is usually more common in women, but so far there are little data available in the literature on sex-specific characteristics regarding this pathology. CSVT is the result of multiple conditions and is therefore to be considered a multifactorial disease where at least one risk factor is present in over 80% of cases. From the literature, we learn that congenital or acquired prothrombotic states are to be considered extremely associated with the occurrence of an acute episode of CSVT and its recurrences. It is, therefore, necessary to fully know the origins and natural history of CSVT, in order to implement the diagnostic and therapeutic pathways of these neurological manifestations. In this report, we summarize the main causes of CSVT considering the possible influence of gender, bearing in mind that most of the causes listed above are pathological conditions closely linked to the female sex.
脑静脉窦血栓形成（CSVT）是一种相对罕见的急性脑循环障碍，但它可能与严重的后遗症和不良预后相关。鉴于其临床表现的极端变异性和细微差别，以及需要适合此类诊断的放射学方法，与之相关的神经学表现往往未得到充分考虑。CSVT通常在女性中更为常见，但迄今为止，关于这种病理的性别特异性特征，文献中几乎没有可用数据。CSVT是多种情况的结果，因此应被视为一种多因素疾病，超过80%的病例中至少存在一种危险因素。从文献中我们了解到，先天性或获得性血栓前状态被认为与CSVT急性发作及其复发的发生极为相关。因此，有必要充分了解CSVT的起源和自然史，以便实施这些神经学表现的诊断和治疗途径。在本报告中，我们总结了CSVT的主要原因，同时考虑到性别的可能影响，要记住上面列出的大多数原因都是与女性密切相关的病理状况。
