孕妇牙周炎：与不良妊娠结局的潜在关联
Periodontitis in Pregnant Women: A Possible Link to Adverse Pregnancy Outcomes.
作者信息
Butera Andrea, Maiorani Carolina, Morandini Annalaura, Trombini Julia, Simonini Manuela, Ogliari Chiara, Scribante Andrea
机构信息
Unit of Dental Hygiene, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.
Member Association: "Mamme & Igieniste", 24125 Bergamo, Italy.
出版信息
Healthcare (Basel). 2023 May 10;11(10):1372. doi: 10.3390/healthcare11101372.
BACKGROUND
Periodontitis develops in 11% of pregnant women, and it is independently linked to severe complications during pregnancy such as preterm birth, low birth weight, and gestational diabetes.
METHODS
A literature search (Pubmed/MEDLINE, and Scopus) from 2003 to 2023 was conducted to analyze studies focused on periodontitis and adverse pregnancy outcomes.
RESULTS
16 articles have been included. Most of the studies showed adverse outcomes, like preterm birth and the low weight of the unborn child, are among the most frequent consequences (respectively 62.5% and 68.7% of articles); pre-eclampsia is also linked to this condition (12.5% of articles); and perinatal mortality (12.5% of articles).
CONCLUSIONS
Periodontal disease appears to be associated with adverse events in pregnancy due to the transport of biofilm bacteria into the bloodstream and into placental tissue; what would cause adverse events is the body's immune response to infection.
背景
11%的孕妇会患牙周炎，且它与孕期严重并发症独立相关，如早产、低出生体重和妊娠期糖尿病。
方法
进行了一项从2003年至2023年的文献检索（PubMed/MEDLINE和Scopus），以分析关注牙周炎和不良妊娠结局的研究。
结果
纳入了16篇文章。大多数研究表明，不良结局，如早产和未出生婴儿体重低，是最常见的后果（分别占文章的62.5%和68.7%）；子痫前期也与这种情况有关（占文章的12.5%）；以及围产期死亡率（占文章的12.5%）。
结论
由于生物膜细菌进入血液循环和胎盘组织，牙周疾病似乎与妊娠不良事件有关；导致不良事件的原因是身体对感染的免疫反应。
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