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[紫外线A对视网膜中褪黑素生物合成的影响]

[Effect of UVA on biosynthesis of melatonin in the retina].

作者信息

Cremer-Bartels G, Krause K

出版信息

Klin Monbl Augenheilkd. 1986 Apr;188(4):295-8. doi: 10.1055/s-2008-1050633.

DOI:10.1055/s-2008-1050633
PMID:3723970
Abstract

No difference in the retinal acetylserotonin-methyltransferase was found in two groups of quail which were exposed to irradiation of 0.1 W/m2 with green and blue light respectively for 1 hour. Decreased retinal enzyme activities (isoelectric point pH 5.0) were observed in response to exposure to green and UVA light concomitantly with increased irradiation. Retinal enzyme activity in response to blue light was lower than in response to UVA light (0.1 W/m2). Although exposure to UVA light affects the visual process only slightly, melatonin biosynthesis was shown to be influenced significantly. Since melatonin is said to play an important role in light adaptation processes, it may be suggested that an imbalance between visual process and light adaptation may occur, predominantly in the aphakic eye.

摘要

分别用绿光和蓝光以0.1 W/m²的强度照射鹌鹑1小时,结果发现两组鹌鹑视网膜中的乙酰血清素甲基转移酶没有差异。随着照射强度增加,同时暴露于绿光和UVA光下时,观察到视网膜酶活性(等电点pH 5.0)降低。蓝光照射后的视网膜酶活性低于UVA光(0.1 W/m²)照射后的活性。虽然UVA光对视觉过程的影响很小,但褪黑素的生物合成受到了显著影响。由于据说褪黑素在光适应过程中起重要作用,因此可能表明主要在无晶状体眼中会出现视觉过程与光适应之间的失衡。

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1
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