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通过对随机临床试验的系统评价和荟萃分析,分析不同类型运动对慢性阻塞性肺疾病(COPD)成人患者呼吸困难和疲劳的影响。

Analysing the Effects of Different Types of Exercise on Dyspnoea and Fatigue in Adults through COPD-Systematic Review and Meta-Analysis of Randomised Clinical Trials.

作者信息

Couto Nuno, Cid Luís, Alves Susana, Brito João Paulo, Pimenta Nuno, Bento Teresa

机构信息

Sport Sciences School of Rio Maior, Polytechnic of Santarém (ESDRM-IPSantarém), 2040-413 Rio Maior, Portugal.

Research Center in Sports Sciences, Health Sciences and Human Development (CIDESD), 5000-556 Vila Real, Portugal.

出版信息

Healthcare (Basel). 2023 May 16;11(10):1449. doi: 10.3390/healthcare11101449.

DOI:10.3390/healthcare11101449
PMID:37239735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10218415/
Abstract

BACKGROUND

Chronic obstructive pulmonary disease (COPD) is a heterogeneous lung condition, the main symptoms of which are dyspnoea and fatigue. Though exercise has been recommended for subjects with COPD, its benefits remain unclear. The aim of this study was to summarise, through a systematic review and meta-analysis, the available evidence on the effects of aerobic, resistance, stretching, and combined exercise on the main symptoms of COPD.

METHODS

Search was performed using the electronic databases PubMed and Web of Science. Randomised controlled trials (RCTs) with interventions based on aerobic, resistance and/or combined exercise published until July 2022 were identified. The effects were summarised based on standardised mean differences (95% confidence intervals) using random and fixed effect models.

RESULTS

Eight studies were selected, including a total of 375 subjects. The results obtained showed that resistance exercise, aerobic exercise and combined exercise seem to improve dyspnoea and fatigue symptoms in COPD subjects.

CONCLUSIONS

In general, we can conclude that exercise-based interventions appear to improve the main COPD symptoms and may benefit quality of life in this population.

摘要

背景

慢性阻塞性肺疾病(COPD)是一种异质性肺部疾病,其主要症状为呼吸困难和疲劳。尽管已建议COPD患者进行运动,但其益处仍不明确。本研究的目的是通过系统评价和荟萃分析,总结有氧运动、抗阻运动、伸展运动及联合运动对COPD主要症状影响的现有证据。

方法

使用电子数据库PubMed和Web of Science进行检索。纳入截至2022年7月发表的、基于有氧运动、抗阻运动和/或联合运动干预的随机对照试验(RCT)。使用随机效应模型和固定效应模型,基于标准化均数差(95%置信区间)总结效应。

结果

共纳入8项研究,总计375名受试者。结果显示,抗阻运动、有氧运动及联合运动似乎可改善COPD患者的呼吸困难和疲劳症状。

结论

总体而言,我们可以得出结论,基于运动的干预措施似乎可改善COPD的主要症状,并可能有益于该人群的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca36/10218415/b79a0707b60d/healthcare-11-01449-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca36/10218415/9e488a0c7168/healthcare-11-01449-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca36/10218415/f2ea3b63cb81/healthcare-11-01449-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca36/10218415/f92fc1d36b53/healthcare-11-01449-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca36/10218415/a3d6b7b1a83f/healthcare-11-01449-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca36/10218415/b79a0707b60d/healthcare-11-01449-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca36/10218415/9e488a0c7168/healthcare-11-01449-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca36/10218415/f2ea3b63cb81/healthcare-11-01449-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca36/10218415/f92fc1d36b53/healthcare-11-01449-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca36/10218415/a3d6b7b1a83f/healthcare-11-01449-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca36/10218415/b79a0707b60d/healthcare-11-01449-g005.jpg

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