Navas-Otero Alba, Calvache-Mateo Andrés, Martín-Núñez Javier, Calles-Plata Irene, Ortiz-Rubio Araceli, Valenza Marie Carmen, López Laura López
Physical Therapy Department, Faculty of Health Sciences, University of Granada, 18016 Granada, Spain.
Healthcare (Basel). 2023 May 18;11(10):1468. doi: 10.3390/healthcare11101468.
The aim of this study was to compare the prevalence of risk factors for frailty between perimenopausal women with long COVID-19 syndrome, women having successfully recovered from COVID-19, and controls from the community. Women with a diagnosis of long COVID-19 and at least one symptom related to the perimenopausal period, women who had successfully recovered from COVID-19, and healthy women of comparable age were included in this study. Symptom severity and functional disability were assessed with the COVID-19 Yorkshire Rehabilitation Scale, and the presence of frailty was evaluated considering the Fried criteria. A total of 195 women were included in the study, distributed over the three groups. The long COVID-19 group showed a higher prevalence of perimenopausal symptoms and impact of COVID-19. Statistically significant differences were found between the long COVID-19 group and the other two groups for the frailty variables. When studying the associations between frailty variables and COVID-19 symptom impact, significant positive correlations were found. Perimenopausal women with long COVID-19 syndrome present more frailty-related factors and experience a higher range of debilitating ongoing symptoms. A significant relationship is shown to exist between long COVID-19 syndrome-related disability and symptoms and frailty variables, resulting in an increased chance of presenting disability.
本研究的目的是比较患有长期新冠综合征的围绝经期女性、已从新冠中成功康复的女性以及社区对照组中衰弱风险因素的患病率。本研究纳入了诊断为长期新冠且至少有一种与围绝经期相关症状的女性、已从新冠中成功康复的女性以及年龄相仿的健康女性。使用新冠约克郡康复量表评估症状严重程度和功能残疾情况，并根据弗里德标准评估衰弱情况。共有195名女性纳入本研究，分布在三组中。长期新冠组围绝经期症状的患病率和新冠的影响更高。在衰弱变量方面，长期新冠组与其他两组之间存在统计学上的显著差异。在研究衰弱变量与新冠症状影响之间的关联时，发现了显著的正相关。患有长期新冠综合征的围绝经期女性存在更多与衰弱相关的因素，并且经历范围更广的持续衰弱症状。长期新冠综合征相关的残疾和症状与衰弱变量之间存在显著关系，导致出现残疾的几率增加。
